Hierarchical control of enzymatic actuators using DNA-based switchable memories

Naturally evolved regulatory circuits have hierarchical layers of signal generation and processing. Here, the authors emulate these networks using feedback-controlled DNA circuits that convert upstream signaling to downstream enzyme activity in a switchable memories circuit.

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Bibliographic Details
Main Authors: Lenny H. H. Meijer, Alex Joesaar, Erik Steur, Wouter Engelen, Rutger A. van Santen, Maarten Merkx, Tom F. A. de Greef
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/a0c209b4d05a45be9da69efaa3c73650
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