Structural and phylogenetic analyses of resistance to next-generation aminoglycosides conferred by AAC(2′) enzymes
Abstract Plazomicin is currently the only next-generation aminoglycoside approved for clinical use that has the potential of evading the effects of widespread enzymatic resistance factors. However, plazomicin is still susceptible to the action of the resistance enzyme AAC(2′)-Ia from Providencia stu...
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Autores principales: | Angelia V. Bassenden, Linda Dumalo, Jaeok Park, Jonathan Blanchet, Krishnagopal Maiti, Dev P. Arya, Albert M. Berghuis |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/a0c86b251ae74d7bb3c137708fa1bbd2 |
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