Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability
Endothelial to mesenchymal transition (EndMT) is a crucial developmental process that also plays a role in the pathogenesis of some diseases. Here the authors show that EndMT contributes to the development of atherosclerosis in mice and humans, and is associated with complex human plaques that may b...
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Nature Portfolio
2016
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oai:doaj.org-article:a0cca03eebdd4de2a5b3919ef6865a762021-12-02T17:32:21ZEndothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability10.1038/ncomms118532041-1723https://doaj.org/article/a0cca03eebdd4de2a5b3919ef6865a762016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11853https://doaj.org/toc/2041-1723Endothelial to mesenchymal transition (EndMT) is a crucial developmental process that also plays a role in the pathogenesis of some diseases. Here the authors show that EndMT contributes to the development of atherosclerosis in mice and humans, and is associated with complex human plaques that may be prone to rupture.Solene M. EvrardLaura LecceKatherine C. MichelisAya Nomura-KitabayashiGaurav PandeyK-Raman PurushothamanValentina d’EscamardJennifer R. LiLahouaria HadriKenji FujitaniPedro R. MorenoLudovic BenardPauline RimmeleAriella CohainBrigham MechamGwendalyn J. RandolphElizabeth G. NabelRoger HajjarValentin FusterManfred BoehmJason C. KovacicNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016) |
| institution |
DOAJ |
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DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Solene M. Evrard Laura Lecce Katherine C. Michelis Aya Nomura-Kitabayashi Gaurav Pandey K-Raman Purushothaman Valentina d’Escamard Jennifer R. Li Lahouaria Hadri Kenji Fujitani Pedro R. Moreno Ludovic Benard Pauline Rimmele Ariella Cohain Brigham Mecham Gwendalyn J. Randolph Elizabeth G. Nabel Roger Hajjar Valentin Fuster Manfred Boehm Jason C. Kovacic Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability |
| description |
Endothelial to mesenchymal transition (EndMT) is a crucial developmental process that also plays a role in the pathogenesis of some diseases. Here the authors show that EndMT contributes to the development of atherosclerosis in mice and humans, and is associated with complex human plaques that may be prone to rupture. |
| format |
article |
| author |
Solene M. Evrard Laura Lecce Katherine C. Michelis Aya Nomura-Kitabayashi Gaurav Pandey K-Raman Purushothaman Valentina d’Escamard Jennifer R. Li Lahouaria Hadri Kenji Fujitani Pedro R. Moreno Ludovic Benard Pauline Rimmele Ariella Cohain Brigham Mecham Gwendalyn J. Randolph Elizabeth G. Nabel Roger Hajjar Valentin Fuster Manfred Boehm Jason C. Kovacic |
| author_facet |
Solene M. Evrard Laura Lecce Katherine C. Michelis Aya Nomura-Kitabayashi Gaurav Pandey K-Raman Purushothaman Valentina d’Escamard Jennifer R. Li Lahouaria Hadri Kenji Fujitani Pedro R. Moreno Ludovic Benard Pauline Rimmele Ariella Cohain Brigham Mecham Gwendalyn J. Randolph Elizabeth G. Nabel Roger Hajjar Valentin Fuster Manfred Boehm Jason C. Kovacic |
| author_sort |
Solene M. Evrard |
| title |
Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability |
| title_short |
Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability |
| title_full |
Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability |
| title_fullStr |
Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability |
| title_full_unstemmed |
Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability |
| title_sort |
endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/a0cca03eebdd4de2a5b3919ef6865a76 |
| work_keys_str_mv |
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