Overexpression of <i>Plasmodium falciparum</i> M1 Aminopeptidase Promotes an Increase in Intracellular Proteolysis and Modifies the Asexual Erythrocytic Cycle Development

Overexpression of <i>Plasmodium falciparum</i> M1 Aminopeptidase Promotes an Increase in Intracellular Proteolysis and Modifies the Asexual Erythrocytic Cycle Development

<i>Plasmodium falciparum</i>, the most virulent of the human malaria parasite, is responsible for high mortality rates worldwide. We studied the M1 alanyl-aminopeptidase of this protozoan (PfA-M1), which is involved in the final stages of hemoglobin cleavage, an essential process for par...

Full description

Saved in:
Bibliographic Details
Main Authors: Carolina C. Hoff, Mauro F. Azevedo, Adriana B. Thurler, Sarah El Chamy Maluf, Pollyana M. S. Melo, Maday Alonso del Rivero, Jorge González-Bacerio, Adriana K. Carmona, Alexandre Budu, Marcos L. Gazarini
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
<i>Plasmodium falciparum</i>
malaria
M1 alanyl-aminopeptidase
antimalarial
PfA-M1 overexpression
Medicine
R
Online Access:https://doaj.org/article/a0d20a6310e044c2a2d8837dadf331db
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/a0d20a6310e044c2a2d8837dadf331db

Similar Items