Clinical, Hematobiochemical And Trace-Elements Alterations In Camels With Sarcoptic Mange (Sarcoptes Scabiei Var Cameli) Accompanied By Secondary Pyoderma

Effects of non-steroidal aromatase inhibitor letrozole on ovarian function in ewe were investigated through testing the hypothesis that letrozole will arrest the growth of dominant follicles, resulting in the emergence of a new follicular wave at a predictable post-treatment interval. Treatment ewes...

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Autores principales:	Abdel Dayem M. A., Hassan M., Fadel M., Senosy W.
Formato:	article
Lenguaje:	EN
Publicado:	Egyptian Society for Animal Management 2020
Materias:	aromatase inhibitor letrozole ewe synchronization estradiol Zoology QL1-991 Veterinary medicine SF600-1100 Animal biochemistry QP501-801
Acceso en línea:	https://dx.doi.org/10.21608/javs.2020.97600 https://doaj.org/article/a0d2dc4bee3d45f0b1e68472cf047cb5
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spelling	oai:doaj.org-article:a0d2dc4bee3d45f0b1e68472cf047cb52021-12-02T14:02:57ZClinical, Hematobiochemical And Trace-Elements Alterations In Camels With Sarcoptic Mange (Sarcoptes Scabiei Var Cameli) Accompanied By Secondary Pyodermahttps://dx.doi.org/10.21608/javs.2020.976001687-40722090-3308https://doaj.org/article/a0d2dc4bee3d45f0b1e68472cf047cb52020-10-01T00:00:00Zhttps://javs.journals.ekb.eg/article_97600.htmlhttps://doaj.org/toc/1687-4072https://doaj.org/toc/2090-3308Effects of non-steroidal aromatase inhibitor letrozole on ovarian function in ewe were investigated through testing the hypothesis that letrozole will arrest the growth of dominant follicles, resulting in the emergence of a new follicular wave at a predictable post-treatment interval. Treatment ewes (n = 10) were treated using an intravaginal sponge (regardless of the stage of estrus) containing 7.5 mg letrozole for five days followed by prostaglandin injection. The control group (n = 10) was treated with gonadotropin prostaglandin gonadotropin (GPG) protocol for ovarian synchronization. Ovarian structures were daily monitored with trans rectal ultrasonography concomitant with blood sampling. Commercial enzyme-linked immunosorbent assay Kits assigned steroid concentration of estradiol, testosterone and progesterone. Some biochemical parameters including blood glucose, total proteins, lipid profiles were measured as a preliminary screening for the effect of applied letrozole treatment on ewes general health condition. Treatment with letrozole decreased serum concentrations of estradiol during sponge insert in the vagina while its concentration increased following removal correlated with the number of ovulatory follicles. On the other hand, the concentration of Progesterone increased correlated with increased number and diameter of corpora lutea resulting from increased diameter and number of ovulatory follicles. The onset of estrus was about 54.00 ± 0.40 hrs. After sponge removal and continued for 25.17 ± 0.24 hrs. Ovulation was synchronous and occurred at 78.70 ± 0.21 hrs after sponge removal. There was no effect of letrozole treatment on measured metabolic parameters. We concluded that letrozole proved to have potential as a non-steroidal treatment for controlling ovarian function and onset of estrus in the ewe. Abdel Dayem M. A.Hassan M.Fadel M.Senosy W.Egyptian Society for Animal Managementarticlearomatase inhibitorletrozoleewesynchronizationestradiolZoologyQL1-991Veterinary medicineSF600-1100Animal biochemistryQP501-801ENJournal of Applied Veterinary Sciences, Vol 5, Iss 4, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	aromatase inhibitor letrozole ewe synchronization estradiol Zoology QL1-991 Veterinary medicine SF600-1100 Animal biochemistry QP501-801
spellingShingle	aromatase inhibitor letrozole ewe synchronization estradiol Zoology QL1-991 Veterinary medicine SF600-1100 Animal biochemistry QP501-801 Abdel Dayem M. A. Hassan M. Fadel M. Senosy W. Clinical, Hematobiochemical And Trace-Elements Alterations In Camels With Sarcoptic Mange (Sarcoptes Scabiei Var Cameli) Accompanied By Secondary Pyoderma
description	Effects of non-steroidal aromatase inhibitor letrozole on ovarian function in ewe were investigated through testing the hypothesis that letrozole will arrest the growth of dominant follicles, resulting in the emergence of a new follicular wave at a predictable post-treatment interval. Treatment ewes (n = 10) were treated using an intravaginal sponge (regardless of the stage of estrus) containing 7.5 mg letrozole for five days followed by prostaglandin injection. The control group (n = 10) was treated with gonadotropin prostaglandin gonadotropin (GPG) protocol for ovarian synchronization. Ovarian structures were daily monitored with trans rectal ultrasonography concomitant with blood sampling. Commercial enzyme-linked immunosorbent assay Kits assigned steroid concentration of estradiol, testosterone and progesterone. Some biochemical parameters including blood glucose, total proteins, lipid profiles were measured as a preliminary screening for the effect of applied letrozole treatment on ewes general health condition. Treatment with letrozole decreased serum concentrations of estradiol during sponge insert in the vagina while its concentration increased following removal correlated with the number of ovulatory follicles. On the other hand, the concentration of Progesterone increased correlated with increased number and diameter of corpora lutea resulting from increased diameter and number of ovulatory follicles. The onset of estrus was about 54.00 ± 0.40 hrs. After sponge removal and continued for 25.17 ± 0.24 hrs. Ovulation was synchronous and occurred at 78.70 ± 0.21 hrs after sponge removal. There was no effect of letrozole treatment on measured metabolic parameters. We concluded that letrozole proved to have potential as a non-steroidal treatment for controlling ovarian function and onset of estrus in the ewe.
format	article
author	Abdel Dayem M. A. Hassan M. Fadel M. Senosy W.
author_facet	Abdel Dayem M. A. Hassan M. Fadel M. Senosy W.
author_sort	Abdel Dayem M. A.
title	Clinical, Hematobiochemical And Trace-Elements Alterations In Camels With Sarcoptic Mange (Sarcoptes Scabiei Var Cameli) Accompanied By Secondary Pyoderma
title_short	Clinical, Hematobiochemical And Trace-Elements Alterations In Camels With Sarcoptic Mange (Sarcoptes Scabiei Var Cameli) Accompanied By Secondary Pyoderma
title_full	Clinical, Hematobiochemical And Trace-Elements Alterations In Camels With Sarcoptic Mange (Sarcoptes Scabiei Var Cameli) Accompanied By Secondary Pyoderma
title_fullStr	Clinical, Hematobiochemical And Trace-Elements Alterations In Camels With Sarcoptic Mange (Sarcoptes Scabiei Var Cameli) Accompanied By Secondary Pyoderma
title_full_unstemmed	Clinical, Hematobiochemical And Trace-Elements Alterations In Camels With Sarcoptic Mange (Sarcoptes Scabiei Var Cameli) Accompanied By Secondary Pyoderma
title_sort	clinical, hematobiochemical and trace-elements alterations in camels with sarcoptic mange (sarcoptes scabiei var cameli) accompanied by secondary pyoderma
publisher	Egyptian Society for Animal Management
publishDate	2020
url	https://dx.doi.org/10.21608/javs.2020.97600 https://doaj.org/article/a0d2dc4bee3d45f0b1e68472cf047cb5
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Clinical, Hematobiochemical And Trace-Elements Alterations In Camels With Sarcoptic Mange (Sarcoptes Scabiei Var Cameli) Accompanied By Secondary Pyoderma

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