Effect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture
The research was carried out on 9 rabbits (males) of Chinchilla breed with modeling of standard perforating fracture of femoral bone. We performed intraosseous introduction of nanocomposite elemental selenium and heteropolysaccharide arabinogalactan 50 mg Se/kg to individuals of experimental group (...
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Scientific Сentre for Family Health and Human Reproduction Problems
2016
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oai:doaj.org-article:a0e1fdbbcb1141ea99650aa4b78bcac22021-11-23T06:14:35ZEffect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture2541-94202587-959610.12737/22978https://doaj.org/article/a0e1fdbbcb1141ea99650aa4b78bcac22016-07-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/251https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The research was carried out on 9 rabbits (males) of Chinchilla breed with modeling of standard perforating fracture of femoral bone. We performed intraosseous introduction of nanocomposite elemental selenium and heteropolysaccharide arabinogalactan 50 mg Se/kg to individuals of experimental group (n = 3) and NaCl 0,9 % to individuals of control group (n = 6). It was established that local intraosseous introduction of the nanocomposite with perforated fracture model did not affect basal metabolic indicators (body temperature, oxygen consumption, carbon dioxide production), but boosted the metabolic processes in the area of the surgical wound from the 9th to 21st days. It proves the bioavailability of the drug and the possibility of creating a local depot of selenium using a nanocomposite.L. V. RodionovaI. A. ShuryginaL. G. SamoylovaB. G. SukhovM. G. ShuryginScientific Сentre for Family Health and Human Reproduction Problemsarticleselenium nanocompositereparative regenerationbasal metabolismthermographybone fractureScienceQRUActa Biomedica Scientifica, Vol 1, Iss 4, Pp 104-108 (2016) |
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DOAJ |
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DOAJ |
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RU |
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selenium nanocomposite reparative regeneration basal metabolism thermography bone fracture Science Q |
| spellingShingle |
selenium nanocomposite reparative regeneration basal metabolism thermography bone fracture Science Q L. V. Rodionova I. A. Shurygina L. G. Samoylova B. G. Sukhov M. G. Shurygin Effect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture |
| description |
The research was carried out on 9 rabbits (males) of Chinchilla breed with modeling of standard perforating fracture of femoral bone. We performed intraosseous introduction of nanocomposite elemental selenium and heteropolysaccharide arabinogalactan 50 mg Se/kg to individuals of experimental group (n = 3) and NaCl 0,9 % to individuals of control group (n = 6). It was established that local intraosseous introduction of the nanocomposite with perforated fracture model did not affect basal metabolic indicators (body temperature, oxygen consumption, carbon dioxide production), but boosted the metabolic processes in the area of the surgical wound from the 9th to 21st days. It proves the bioavailability of the drug and the possibility of creating a local depot of selenium using a nanocomposite. |
| format |
article |
| author |
L. V. Rodionova I. A. Shurygina L. G. Samoylova B. G. Sukhov M. G. Shurygin |
| author_facet |
L. V. Rodionova I. A. Shurygina L. G. Samoylova B. G. Sukhov M. G. Shurygin |
| author_sort |
L. V. Rodionova |
| title |
Effect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture |
| title_short |
Effect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture |
| title_full |
Effect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture |
| title_fullStr |
Effect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture |
| title_full_unstemmed |
Effect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture |
| title_sort |
effect of intraosseous introduction of selenium/arabinogalactan nanoglycoconjugate on the main indicators of primary metabolism in consolidation of bone fracture |
| publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
| publishDate |
2016 |
| url |
https://doaj.org/article/a0e1fdbbcb1141ea99650aa4b78bcac2 |
| work_keys_str_mv |
AT lvrodionova effectofintraosseousintroductionofseleniumarabinogalactannanoglycoconjugateonthemainindicatorsofprimarymetabolisminconsolidationofbonefracture AT iashurygina effectofintraosseousintroductionofseleniumarabinogalactannanoglycoconjugateonthemainindicatorsofprimarymetabolisminconsolidationofbonefracture AT lgsamoylova effectofintraosseousintroductionofseleniumarabinogalactannanoglycoconjugateonthemainindicatorsofprimarymetabolisminconsolidationofbonefracture AT bgsukhov effectofintraosseousintroductionofseleniumarabinogalactannanoglycoconjugateonthemainindicatorsofprimarymetabolisminconsolidationofbonefracture AT mgshurygin effectofintraosseousintroductionofseleniumarabinogalactannanoglycoconjugateonthemainindicatorsofprimarymetabolisminconsolidationofbonefracture |
| _version_ |
1718417023845793792 |