Topical delivery of DNA oligonucleotide to induce p53 generation in the skin via thymidine dinucleotide (pTT)-encapsulated liposomal carrier
Yi-Ping FangDepartment of Biotechnology, Yuanpei University, Hsinchu, TaiwanIntroduction: Transcription factor p53 has a powerful tumor suppressing function that is associated with many cancers. Since the molecular weight of p53 is 53 kDa, it is difficult to transport across cell membranes. Thymidin...
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| Format: | article |
| Langue: | EN |
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Dove Medical Press
2011
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| Accès en ligne: | https://doaj.org/article/a0e66ab29be94501af168e2f34ef4073 |
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