JQ-1 ameliorates schistosomiasis liver fibrosis by suppressing JAK2 and STAT3 activation

Schistosomiasis is a serious parasitic infection caused by Schistosoma. The parasite deposits eggs in the host liver, causing inflammation that activates hepatic stellate cells (HSCs), which leads to liver fibrosis. Currently, there is no effective therapy for liver fibrosis; thus, treatments are ur...

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Auteurs principaux: Han Ding, Xuhan Yang, Jiaming Tian, Xinran Wang, Yongsheng Ji, Saeed El-Ashram, Cuiping Ren, Jijia Shen, Miao Liu
Format: article
Langue:EN
Publié: Elsevier 2021
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Accès en ligne:https://doaj.org/article/a0e897dc1eb44c03aaff0e59bc579fb1
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