Facial Diplegia—Complication or Manifestation of SARS-CoV-2 Infection? A Case Report and Systemic Literature Review

Since the outbreak of the new coronavirus, healthcare systems around the world have witnessed not only COVID-19 symptoms but also long-term complications of the aforementioned, including neurological problems. We report a clinical case of an adult patient with bilateral facial nerve palsy and progre...

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Autores principales:	Anna K. Szewczyk, Urszula Skrobas, Anna Jamroz-Wiśniewska, Krystyna Mitosek-Szewczyk, Konrad Rejdak
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	COVID-19 SARS-CoV-2 Guillain-Barré Syndrome peripheral nervous system disease peripheral facial nerve palsy Bell’s palsy Medicine R
Acceso en línea:	https://doaj.org/article/a0eb16d84fcd4c3f851a28a546013776
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spelling	oai:doaj.org-article:a0eb16d84fcd4c3f851a28a5460137762021-11-25T17:44:55ZFacial Diplegia—Complication or Manifestation of SARS-CoV-2 Infection? A Case Report and Systemic Literature Review10.3390/healthcare91114922227-9032https://doaj.org/article/a0eb16d84fcd4c3f851a28a5460137762021-11-01T00:00:00Zhttps://www.mdpi.com/2227-9032/9/11/1492https://doaj.org/toc/2227-9032Since the outbreak of the new coronavirus, healthcare systems around the world have witnessed not only COVID-19 symptoms but also long-term complications of the aforementioned, including neurological problems. We report a clinical case of an adult patient with bilateral facial nerve palsy and progressive ascending paresis of the limbs after contracting the novel coronavirus (COVID-19). Additionally, the systematic review aimed to identify and summarize specific clinical features, outcomes and complications of the studies focusing on bilateral facial diplegia as a sequela of COVID-19 infection. The total number of analyzed patients was 15. Only one patient was diagnosed with isolated bilateral palsy; the rest had Guillain-Barré Syndrome (GBS). With one exception, all the presented cases had favorable outcomes, with facial palsy recovery from slight to almost complete. In patients with a confirmed COVID-19 diagnosis, bilateral facial palsy may be an isolated symptom as well as a variant of GBS. Symptoms of cranial nerve damage during a COVID-19 infection may explain the appearance of facial nerve damage. In order to clarify the spectrum of neurological manifestations and a causal relation between SARS-CoV-2, COVID-19 vaccination and neurological symptoms, direct attention towards the study of this virus is crucial. It seems reasonable to recognize human coronavirus as another potential GBS trigger.Anna K. SzewczykUrszula SkrobasAnna Jamroz-WiśniewskaKrystyna Mitosek-SzewczykKonrad RejdakMDPI AGarticleCOVID-19SARS-CoV-2Guillain-Barré Syndromeperipheral nervous system diseaseperipheral facial nerve palsyBell’s palsyMedicineRENHealthcare, Vol 9, Iss 1492, p 1492 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID-19 SARS-CoV-2 Guillain-Barré Syndrome peripheral nervous system disease peripheral facial nerve palsy Bell’s palsy Medicine R
spellingShingle	COVID-19 SARS-CoV-2 Guillain-Barré Syndrome peripheral nervous system disease peripheral facial nerve palsy Bell’s palsy Medicine R Anna K. Szewczyk Urszula Skrobas Anna Jamroz-Wiśniewska Krystyna Mitosek-Szewczyk Konrad Rejdak Facial Diplegia—Complication or Manifestation of SARS-CoV-2 Infection? A Case Report and Systemic Literature Review
description	Since the outbreak of the new coronavirus, healthcare systems around the world have witnessed not only COVID-19 symptoms but also long-term complications of the aforementioned, including neurological problems. We report a clinical case of an adult patient with bilateral facial nerve palsy and progressive ascending paresis of the limbs after contracting the novel coronavirus (COVID-19). Additionally, the systematic review aimed to identify and summarize specific clinical features, outcomes and complications of the studies focusing on bilateral facial diplegia as a sequela of COVID-19 infection. The total number of analyzed patients was 15. Only one patient was diagnosed with isolated bilateral palsy; the rest had Guillain-Barré Syndrome (GBS). With one exception, all the presented cases had favorable outcomes, with facial palsy recovery from slight to almost complete. In patients with a confirmed COVID-19 diagnosis, bilateral facial palsy may be an isolated symptom as well as a variant of GBS. Symptoms of cranial nerve damage during a COVID-19 infection may explain the appearance of facial nerve damage. In order to clarify the spectrum of neurological manifestations and a causal relation between SARS-CoV-2, COVID-19 vaccination and neurological symptoms, direct attention towards the study of this virus is crucial. It seems reasonable to recognize human coronavirus as another potential GBS trigger.
format	article
author	Anna K. Szewczyk Urszula Skrobas Anna Jamroz-Wiśniewska Krystyna Mitosek-Szewczyk Konrad Rejdak
author_facet	Anna K. Szewczyk Urszula Skrobas Anna Jamroz-Wiśniewska Krystyna Mitosek-Szewczyk Konrad Rejdak
author_sort	Anna K. Szewczyk
title	Facial Diplegia—Complication or Manifestation of SARS-CoV-2 Infection? A Case Report and Systemic Literature Review
title_short	Facial Diplegia—Complication or Manifestation of SARS-CoV-2 Infection? A Case Report and Systemic Literature Review
title_full	Facial Diplegia—Complication or Manifestation of SARS-CoV-2 Infection? A Case Report and Systemic Literature Review
title_fullStr	Facial Diplegia—Complication or Manifestation of SARS-CoV-2 Infection? A Case Report and Systemic Literature Review
title_full_unstemmed	Facial Diplegia—Complication or Manifestation of SARS-CoV-2 Infection? A Case Report and Systemic Literature Review
title_sort	facial diplegia—complication or manifestation of sars-cov-2 infection? a case report and systemic literature review
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/a0eb16d84fcd4c3f851a28a546013776
work_keys_str_mv	AT annakszewczyk facialdiplegiacomplicationormanifestationofsarscov2infectionacasereportandsystemicliteraturereview AT urszulaskrobas facialdiplegiacomplicationormanifestationofsarscov2infectionacasereportandsystemicliteraturereview AT annajamrozwisniewska facialdiplegiacomplicationormanifestationofsarscov2infectionacasereportandsystemicliteraturereview AT krystynamitosekszewczyk facialdiplegiacomplicationormanifestationofsarscov2infectionacasereportandsystemicliteraturereview AT konradrejdak facialdiplegiacomplicationormanifestationofsarscov2infectionacasereportandsystemicliteraturereview
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Facial Diplegia—Complication or Manifestation of SARS-CoV-2 Infection? A Case Report and Systemic Literature Review

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