Oral absorption and drug interaction kinetics of moxifloxacin in an animal model of weightlessness

Abstract To investigate the effect of simulated weightlessness on the pharmacokinetics of orally administered moxifloxacin and the antacid Maalox or the antidiarrheal Pepto-Bismol using a tail-suspended (TS) rat model of microgravity. Fasted control and TS, jugular-vein-cannulated, male Sprague-Dawl...

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Autores principales: Dong Liang, Jing Ma, Bo Wei
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a0f98b5978a74b73b1d71af73e90edb4
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