Oral absorption and drug interaction kinetics of moxifloxacin in an animal model of weightlessness

Abstract To investigate the effect of simulated weightlessness on the pharmacokinetics of orally administered moxifloxacin and the antacid Maalox or the antidiarrheal Pepto-Bismol using a tail-suspended (TS) rat model of microgravity. Fasted control and TS, jugular-vein-cannulated, male Sprague-Dawl...

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Bibliographic Details
Main Authors: Dong Liang, Jing Ma, Bo Wei
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/a0f98b5978a74b73b1d71af73e90edb4
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