The calcium channel subunit α2δ-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway
Activity-dependent pathways are important for synapse function but the molecular links to synapse function are not clear. The authors show that the Ca2 + channel subunit α2δ-3 provides an extracellular scaffold for autocrine BMP signalling at the Drosophila neuromuscular junction.
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| Autores principales: | , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2019
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/a1043f4b84eb401ca0ba1c3cdf432be5 |
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| Sumario: | Activity-dependent pathways are important for synapse function but the molecular links to synapse function are not clear. The authors show that the Ca2 + channel subunit α2δ-3 provides an extracellular scaffold for autocrine BMP signalling at the Drosophila neuromuscular junction. |
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