The calcium channel subunit α2δ-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway

Activity-dependent pathways are important for synapse function but the molecular links to synapse function are not clear. The authors show that the Ca2 + channel subunit α2δ-3 provides an extracellular scaffold for autocrine BMP signalling at the Drosophila neuromuscular junction.

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Autores principales:	Kendall M. Hoover, Scott J. Gratz, Nova Qi, Kelsey A. Herrmann, Yizhou Liu, Jahci J. Perry-Richardson, Pamela J. Vanderzalm, Kate M. O’Connor-Giles, Heather T. Broihier
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a1043f4b84eb401ca0ba1c3cdf432be5
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spelling	oai:doaj.org-article:a1043f4b84eb401ca0ba1c3cdf432be52021-12-02T14:38:42ZThe calcium channel subunit α2δ-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway10.1038/s41467-019-13165-72041-1723https://doaj.org/article/a1043f4b84eb401ca0ba1c3cdf432be52019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13165-7https://doaj.org/toc/2041-1723Activity-dependent pathways are important for synapse function but the molecular links to synapse function are not clear. The authors show that the Ca2 + channel subunit α2δ-3 provides an extracellular scaffold for autocrine BMP signalling at the Drosophila neuromuscular junction.Kendall M. HooverScott J. GratzNova QiKelsey A. HerrmannYizhou LiuJahci J. Perry-RichardsonPamela J. VanderzalmKate M. O’Connor-GilesHeather T. BroihierNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kendall M. Hoover Scott J. Gratz Nova Qi Kelsey A. Herrmann Yizhou Liu Jahci J. Perry-Richardson Pamela J. Vanderzalm Kate M. O’Connor-Giles Heather T. Broihier The calcium channel subunit α2δ-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway
description	Activity-dependent pathways are important for synapse function but the molecular links to synapse function are not clear. The authors show that the Ca2 + channel subunit α2δ-3 provides an extracellular scaffold for autocrine BMP signalling at the Drosophila neuromuscular junction.
format	article
author	Kendall M. Hoover Scott J. Gratz Nova Qi Kelsey A. Herrmann Yizhou Liu Jahci J. Perry-Richardson Pamela J. Vanderzalm Kate M. O’Connor-Giles Heather T. Broihier
author_facet	Kendall M. Hoover Scott J. Gratz Nova Qi Kelsey A. Herrmann Yizhou Liu Jahci J. Perry-Richardson Pamela J. Vanderzalm Kate M. O’Connor-Giles Heather T. Broihier
author_sort	Kendall M. Hoover
title	The calcium channel subunit α2δ-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway
title_short	The calcium channel subunit α2δ-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway
title_full	The calcium channel subunit α2δ-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway
title_fullStr	The calcium channel subunit α2δ-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway
title_full_unstemmed	The calcium channel subunit α2δ-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway
title_sort	calcium channel subunit α2δ-3 organizes synapses via an activity-dependent and autocrine bmp signaling pathway
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/a1043f4b84eb401ca0ba1c3cdf432be5
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The calcium channel subunit α2δ-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway

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