Local-to-global signal transduction at the core of a Mn2+ sensing riboswitch

Riboswitches bind intracellular metabolites and control bacterial gene expression. Here, by using X-ray crystallography, molecular dynamics simulations, and single-molecule fluorescence resonance energy transfer, the authors show how a local Mn2+ ion-binding signal is transduced across the yybP-ykoY...

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Autores principales:	Krishna C. Suddala, Ian R. Price, Shiba S. Dandpat, Michal Janeček, Petra Kührová, Jiří Šponer, Pavel Banáš, Ailong Ke, Nils G. Walter
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a105e074773f48059aba90c0f77a1c51
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spelling	oai:doaj.org-article:a105e074773f48059aba90c0f77a1c512021-12-02T16:57:35ZLocal-to-global signal transduction at the core of a Mn2+ sensing riboswitch10.1038/s41467-019-12230-52041-1723https://doaj.org/article/a105e074773f48059aba90c0f77a1c512019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12230-5https://doaj.org/toc/2041-1723Riboswitches bind intracellular metabolites and control bacterial gene expression. Here, by using X-ray crystallography, molecular dynamics simulations, and single-molecule fluorescence resonance energy transfer, the authors show how a local Mn2+ ion-binding signal is transduced across the yybP-ykoY riboswitch from Xanthomonas oryzae.Krishna C. SuddalaIan R. PriceShiba S. DandpatMichal JanečekPetra KührováJiří ŠponerPavel BanášAilong KeNils G. WalterNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Krishna C. Suddala Ian R. Price Shiba S. Dandpat Michal Janeček Petra Kührová Jiří Šponer Pavel Banáš Ailong Ke Nils G. Walter Local-to-global signal transduction at the core of a Mn2+ sensing riboswitch
description	Riboswitches bind intracellular metabolites and control bacterial gene expression. Here, by using X-ray crystallography, molecular dynamics simulations, and single-molecule fluorescence resonance energy transfer, the authors show how a local Mn2+ ion-binding signal is transduced across the yybP-ykoY riboswitch from Xanthomonas oryzae.
format	article
author	Krishna C. Suddala Ian R. Price Shiba S. Dandpat Michal Janeček Petra Kührová Jiří Šponer Pavel Banáš Ailong Ke Nils G. Walter
author_facet	Krishna C. Suddala Ian R. Price Shiba S. Dandpat Michal Janeček Petra Kührová Jiří Šponer Pavel Banáš Ailong Ke Nils G. Walter
author_sort	Krishna C. Suddala
title	Local-to-global signal transduction at the core of a Mn2+ sensing riboswitch
title_short	Local-to-global signal transduction at the core of a Mn2+ sensing riboswitch
title_full	Local-to-global signal transduction at the core of a Mn2+ sensing riboswitch
title_fullStr	Local-to-global signal transduction at the core of a Mn2+ sensing riboswitch
title_full_unstemmed	Local-to-global signal transduction at the core of a Mn2+ sensing riboswitch
title_sort	local-to-global signal transduction at the core of a mn2+ sensing riboswitch
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/a105e074773f48059aba90c0f77a1c51
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Local-to-global signal transduction at the core of a Mn2+ sensing riboswitch

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