Local-to-global signal transduction at the core of a Mn2+ sensing riboswitch
Riboswitches bind intracellular metabolites and control bacterial gene expression. Here, by using X-ray crystallography, molecular dynamics simulations, and single-molecule fluorescence resonance energy transfer, the authors show how a local Mn2+ ion-binding signal is transduced across the yybP-ykoY...
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Main Authors: | Krishna C. Suddala, Ian R. Price, Shiba S. Dandpat, Michal Janeček, Petra Kührová, Jiří Šponer, Pavel Banáš, Ailong Ke, Nils G. Walter |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
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Subjects: | |
Online Access: | https://doaj.org/article/a105e074773f48059aba90c0f77a1c51 |
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