Local-to-global signal transduction at the core of a Mn2+ sensing riboswitch

Riboswitches bind intracellular metabolites and control bacterial gene expression. Here, by using X-ray crystallography, molecular dynamics simulations, and single-molecule fluorescence resonance energy transfer, the authors show how a local Mn2+ ion-binding signal is transduced across the yybP-ykoY...

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Bibliographic Details
Main Authors: Krishna C. Suddala, Ian R. Price, Shiba S. Dandpat, Michal Janeček, Petra Kührová, Jiří Šponer, Pavel Banáš, Ailong Ke, Nils G. Walter
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/a105e074773f48059aba90c0f77a1c51
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