Stress gates an astrocytic energy reservoir to impair synaptic plasticity

Enduring changes in synaptic efficacy are highly sensitive to stress. Here, the authors show that astrocytic delivery of metabolites has an important role in the stress-mediated impairment of synaptic plasticity.

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Autores principales: Ciaran Murphy-Royal, April D. Johnston, Andrew K. J. Boyce, Blanca Diaz-Castro, Adam Institoris, Govind Peringod, Oliver Zhang, Randy F. Stout, David C. Spray, Roger J. Thompson, Baljit S. Khakh, Jaideep S. Bains, Grant R. Gordon
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/a10e4cb6fa8941679643d05fade21f65
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spelling oai:doaj.org-article:a10e4cb6fa8941679643d05fade21f652021-12-02T14:42:48ZStress gates an astrocytic energy reservoir to impair synaptic plasticity10.1038/s41467-020-15778-92041-1723https://doaj.org/article/a10e4cb6fa8941679643d05fade21f652020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15778-9https://doaj.org/toc/2041-1723Enduring changes in synaptic efficacy are highly sensitive to stress. Here, the authors show that astrocytic delivery of metabolites has an important role in the stress-mediated impairment of synaptic plasticity.Ciaran Murphy-RoyalApril D. JohnstonAndrew K. J. BoyceBlanca Diaz-CastroAdam InstitorisGovind PeringodOliver ZhangRandy F. StoutDavid C. SprayRoger J. ThompsonBaljit S. KhakhJaideep S. BainsGrant R. GordonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ciaran Murphy-Royal
April D. Johnston
Andrew K. J. Boyce
Blanca Diaz-Castro
Adam Institoris
Govind Peringod
Oliver Zhang
Randy F. Stout
David C. Spray
Roger J. Thompson
Baljit S. Khakh
Jaideep S. Bains
Grant R. Gordon
Stress gates an astrocytic energy reservoir to impair synaptic plasticity
description Enduring changes in synaptic efficacy are highly sensitive to stress. Here, the authors show that astrocytic delivery of metabolites has an important role in the stress-mediated impairment of synaptic plasticity.
format article
author Ciaran Murphy-Royal
April D. Johnston
Andrew K. J. Boyce
Blanca Diaz-Castro
Adam Institoris
Govind Peringod
Oliver Zhang
Randy F. Stout
David C. Spray
Roger J. Thompson
Baljit S. Khakh
Jaideep S. Bains
Grant R. Gordon
author_facet Ciaran Murphy-Royal
April D. Johnston
Andrew K. J. Boyce
Blanca Diaz-Castro
Adam Institoris
Govind Peringod
Oliver Zhang
Randy F. Stout
David C. Spray
Roger J. Thompson
Baljit S. Khakh
Jaideep S. Bains
Grant R. Gordon
author_sort Ciaran Murphy-Royal
title Stress gates an astrocytic energy reservoir to impair synaptic plasticity
title_short Stress gates an astrocytic energy reservoir to impair synaptic plasticity
title_full Stress gates an astrocytic energy reservoir to impair synaptic plasticity
title_fullStr Stress gates an astrocytic energy reservoir to impair synaptic plasticity
title_full_unstemmed Stress gates an astrocytic energy reservoir to impair synaptic plasticity
title_sort stress gates an astrocytic energy reservoir to impair synaptic plasticity
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/a10e4cb6fa8941679643d05fade21f65
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