Stress gates an astrocytic energy reservoir to impair synaptic plasticity
Enduring changes in synaptic efficacy are highly sensitive to stress. Here, the authors show that astrocytic delivery of metabolites has an important role in the stress-mediated impairment of synaptic plasticity.
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Nature Portfolio
2020
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oai:doaj.org-article:a10e4cb6fa8941679643d05fade21f652021-12-02T14:42:48ZStress gates an astrocytic energy reservoir to impair synaptic plasticity10.1038/s41467-020-15778-92041-1723https://doaj.org/article/a10e4cb6fa8941679643d05fade21f652020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15778-9https://doaj.org/toc/2041-1723Enduring changes in synaptic efficacy are highly sensitive to stress. Here, the authors show that astrocytic delivery of metabolites has an important role in the stress-mediated impairment of synaptic plasticity.Ciaran Murphy-RoyalApril D. JohnstonAndrew K. J. BoyceBlanca Diaz-CastroAdam InstitorisGovind PeringodOliver ZhangRandy F. StoutDavid C. SprayRoger J. ThompsonBaljit S. KhakhJaideep S. BainsGrant R. GordonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020) |
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Science Q Ciaran Murphy-Royal April D. Johnston Andrew K. J. Boyce Blanca Diaz-Castro Adam Institoris Govind Peringod Oliver Zhang Randy F. Stout David C. Spray Roger J. Thompson Baljit S. Khakh Jaideep S. Bains Grant R. Gordon Stress gates an astrocytic energy reservoir to impair synaptic plasticity |
description |
Enduring changes in synaptic efficacy are highly sensitive to stress. Here, the authors show that astrocytic delivery of metabolites has an important role in the stress-mediated impairment of synaptic plasticity. |
format |
article |
author |
Ciaran Murphy-Royal April D. Johnston Andrew K. J. Boyce Blanca Diaz-Castro Adam Institoris Govind Peringod Oliver Zhang Randy F. Stout David C. Spray Roger J. Thompson Baljit S. Khakh Jaideep S. Bains Grant R. Gordon |
author_facet |
Ciaran Murphy-Royal April D. Johnston Andrew K. J. Boyce Blanca Diaz-Castro Adam Institoris Govind Peringod Oliver Zhang Randy F. Stout David C. Spray Roger J. Thompson Baljit S. Khakh Jaideep S. Bains Grant R. Gordon |
author_sort |
Ciaran Murphy-Royal |
title |
Stress gates an astrocytic energy reservoir to impair synaptic plasticity |
title_short |
Stress gates an astrocytic energy reservoir to impair synaptic plasticity |
title_full |
Stress gates an astrocytic energy reservoir to impair synaptic plasticity |
title_fullStr |
Stress gates an astrocytic energy reservoir to impair synaptic plasticity |
title_full_unstemmed |
Stress gates an astrocytic energy reservoir to impair synaptic plasticity |
title_sort |
stress gates an astrocytic energy reservoir to impair synaptic plasticity |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/a10e4cb6fa8941679643d05fade21f65 |
work_keys_str_mv |
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1718389586105729024 |