Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation

Imiquimod exacerbates IL-23-induced skin inflammation and models psoriasis in mice. Here the authors show that this pathology is not dependent on resident dendritic cells, but on CCR6-induced immigration of monocyte-derived cells.

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Autores principales:	Tej Pratap Singh, Howard H. Zhang, Izabela Borek, Peter Wolf, Michael N. Hedrick, Satya P. Singh, Brian L. Kelsall, Bjorn E. Clausen, Joshua M. Farber
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a126aabdb97548dbabecf0921d638839
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spelling	oai:doaj.org-article:a126aabdb97548dbabecf0921d6388392021-12-02T14:39:30ZMonocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation10.1038/ncomms135812041-1723https://doaj.org/article/a126aabdb97548dbabecf0921d6388392016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13581https://doaj.org/toc/2041-1723Imiquimod exacerbates IL-23-induced skin inflammation and models psoriasis in mice. Here the authors show that this pathology is not dependent on resident dendritic cells, but on CCR6-induced immigration of monocyte-derived cells.Tej Pratap SinghHoward H. ZhangIzabela BorekPeter WolfMichael N. HedrickSatya P. SinghBrian L. KelsallBjorn E. ClausenJoshua M. FarberNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-18 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tej Pratap Singh Howard H. Zhang Izabela Borek Peter Wolf Michael N. Hedrick Satya P. Singh Brian L. Kelsall Bjorn E. Clausen Joshua M. Farber Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation
description	Imiquimod exacerbates IL-23-induced skin inflammation and models psoriasis in mice. Here the authors show that this pathology is not dependent on resident dendritic cells, but on CCR6-induced immigration of monocyte-derived cells.
format	article
author	Tej Pratap Singh Howard H. Zhang Izabela Borek Peter Wolf Michael N. Hedrick Satya P. Singh Brian L. Kelsall Bjorn E. Clausen Joshua M. Farber
author_facet	Tej Pratap Singh Howard H. Zhang Izabela Borek Peter Wolf Michael N. Hedrick Satya P. Singh Brian L. Kelsall Bjorn E. Clausen Joshua M. Farber
author_sort	Tej Pratap Singh
title	Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation
title_short	Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation
title_full	Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation
title_fullStr	Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation
title_full_unstemmed	Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation
title_sort	monocyte-derived inflammatory langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/a126aabdb97548dbabecf0921d638839
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Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation

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