PEGylated graphene oxide elicits strong immunological responses despite surface passivation

Polyethylene glycol has been widely utilized to functionalize nanomaterials in order to improve their biocompatibility. Here, the authors demonstrate that PEGylated nano-graphene oxide can elicit an inflammatory response, contradicting current literature.

Guardado en:
Detalles Bibliográficos
Autores principales: Nana Luo, Jeffrey K. Weber, Shuang Wang, Binquan Luan, Hua Yue, Xiaobo Xi, Jing Du, Zaixing Yang, Wei Wei, Ruhong Zhou, Guanghui Ma
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/a128b2d6b00b4f8f896db220436e5a4a
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:a128b2d6b00b4f8f896db220436e5a4a
record_format dspace
spelling oai:doaj.org-article:a128b2d6b00b4f8f896db220436e5a4a2021-12-02T15:38:41ZPEGylated graphene oxide elicits strong immunological responses despite surface passivation10.1038/ncomms145372041-1723https://doaj.org/article/a128b2d6b00b4f8f896db220436e5a4a2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14537https://doaj.org/toc/2041-1723Polyethylene glycol has been widely utilized to functionalize nanomaterials in order to improve their biocompatibility. Here, the authors demonstrate that PEGylated nano-graphene oxide can elicit an inflammatory response, contradicting current literature.Nana LuoJeffrey K. WeberShuang WangBinquan LuanHua YueXiaobo XiJing DuZaixing YangWei WeiRuhong ZhouGuanghui MaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Nana Luo
Jeffrey K. Weber
Shuang Wang
Binquan Luan
Hua Yue
Xiaobo Xi
Jing Du
Zaixing Yang
Wei Wei
Ruhong Zhou
Guanghui Ma
PEGylated graphene oxide elicits strong immunological responses despite surface passivation
description Polyethylene glycol has been widely utilized to functionalize nanomaterials in order to improve their biocompatibility. Here, the authors demonstrate that PEGylated nano-graphene oxide can elicit an inflammatory response, contradicting current literature.
format article
author Nana Luo
Jeffrey K. Weber
Shuang Wang
Binquan Luan
Hua Yue
Xiaobo Xi
Jing Du
Zaixing Yang
Wei Wei
Ruhong Zhou
Guanghui Ma
author_facet Nana Luo
Jeffrey K. Weber
Shuang Wang
Binquan Luan
Hua Yue
Xiaobo Xi
Jing Du
Zaixing Yang
Wei Wei
Ruhong Zhou
Guanghui Ma
author_sort Nana Luo
title PEGylated graphene oxide elicits strong immunological responses despite surface passivation
title_short PEGylated graphene oxide elicits strong immunological responses despite surface passivation
title_full PEGylated graphene oxide elicits strong immunological responses despite surface passivation
title_fullStr PEGylated graphene oxide elicits strong immunological responses despite surface passivation
title_full_unstemmed PEGylated graphene oxide elicits strong immunological responses despite surface passivation
title_sort pegylated graphene oxide elicits strong immunological responses despite surface passivation
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/a128b2d6b00b4f8f896db220436e5a4a
work_keys_str_mv AT nanaluo pegylatedgrapheneoxideelicitsstrongimmunologicalresponsesdespitesurfacepassivation
AT jeffreykweber pegylatedgrapheneoxideelicitsstrongimmunologicalresponsesdespitesurfacepassivation
AT shuangwang pegylatedgrapheneoxideelicitsstrongimmunologicalresponsesdespitesurfacepassivation
AT binquanluan pegylatedgrapheneoxideelicitsstrongimmunologicalresponsesdespitesurfacepassivation
AT huayue pegylatedgrapheneoxideelicitsstrongimmunologicalresponsesdespitesurfacepassivation
AT xiaoboxi pegylatedgrapheneoxideelicitsstrongimmunologicalresponsesdespitesurfacepassivation
AT jingdu pegylatedgrapheneoxideelicitsstrongimmunologicalresponsesdespitesurfacepassivation
AT zaixingyang pegylatedgrapheneoxideelicitsstrongimmunologicalresponsesdespitesurfacepassivation
AT weiwei pegylatedgrapheneoxideelicitsstrongimmunologicalresponsesdespitesurfacepassivation
AT ruhongzhou pegylatedgrapheneoxideelicitsstrongimmunologicalresponsesdespitesurfacepassivation
AT guanghuima pegylatedgrapheneoxideelicitsstrongimmunologicalresponsesdespitesurfacepassivation
_version_ 1718386131120160768