High dose of histone deacetylase inhibitors affects insulin secretory mechanism of pancreatic beta cell line
Objective. Histone deacytylase inhibitors (HDACis) inhibit the deacetylation of the lysine residue of proteins, including histones, and regulate the transcription of a variety of genes. Recently, HDACis have been used clinically as anti-cancer drugs and possible anti-diabetic drugs. Even though HDAC...
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| Format: | article |
| Langue: | EN |
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Sciendo
2018
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| Accès en ligne: | https://doaj.org/article/a1331ef46d6d46e983349cdeb35e1fdb |
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