Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection

Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection

SARS-CoV-2 infection of expecting mothers has been reported. Here the authors profile the peripheral blood from 14 pregnant women with asymptomatic or mild SARS-CoV-2 infection to find grossly normal immune cell composition but heterogenous induction of pro-inflammatory cytokines, thereby implicatin...

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Autores principales: Sara De Biasi, Domenico Lo Tartaro, Lara Gibellini, Annamaria Paolini, Andrew Quong, Carlene Petes, Geneve Awong, Samuel Douglas, Dongxia Lin, Jordan Nieto, Francesco Maria Galassi, Rebecca Borella, Lucia Fidanza, Marco Mattioli, Chiara Leone, Isabella Neri, Marianna Meschiari, Luca Cicchetti, Anna Iannone, Tommaso Trenti, Mario Sarti, Massimo Girardis, Giovanni Guaraldi, Cristina Mussini, Fabio Facchinetti, Andrea Cossarizza
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/a1354789176743538389b83400e3252c
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Sumario:SARS-CoV-2 infection of expecting mothers has been reported. Here the authors profile the peripheral blood from 14 pregnant women with asymptomatic or mild SARS-CoV-2 infection to find grossly normal immune cell composition but heterogenous induction of pro-inflammatory cytokines, thereby implicating possible therapeutic targets for virus-induced damages during pregnancy.

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