Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection

Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection

SARS-CoV-2 infection of expecting mothers has been reported. Here the authors profile the peripheral blood from 14 pregnant women with asymptomatic or mild SARS-CoV-2 infection to find grossly normal immune cell composition but heterogenous induction of pro-inflammatory cytokines, thereby implicatin...

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Autores principales: Sara De Biasi, Domenico Lo Tartaro, Lara Gibellini, Annamaria Paolini, Andrew Quong, Carlene Petes, Geneve Awong, Samuel Douglas, Dongxia Lin, Jordan Nieto, Francesco Maria Galassi, Rebecca Borella, Lucia Fidanza, Marco Mattioli, Chiara Leone, Isabella Neri, Marianna Meschiari, Luca Cicchetti, Anna Iannone, Tommaso Trenti, Mario Sarti, Massimo Girardis, Giovanni Guaraldi, Cristina Mussini, Fabio Facchinetti, Andrea Cossarizza
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/a1354789176743538389b83400e3252c
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spelling oai:doaj.org-article:a1354789176743538389b83400e3252c2021-12-02T16:14:24ZEndogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection10.1038/s41467-021-24940-w2041-1723https://doaj.org/article/a1354789176743538389b83400e3252c2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24940-whttps://doaj.org/toc/2041-1723SARS-CoV-2 infection of expecting mothers has been reported. Here the authors profile the peripheral blood from 14 pregnant women with asymptomatic or mild SARS-CoV-2 infection to find grossly normal immune cell composition but heterogenous induction of pro-inflammatory cytokines, thereby implicating possible therapeutic targets for virus-induced damages during pregnancy.Sara De BiasiDomenico Lo TartaroLara GibelliniAnnamaria PaoliniAndrew QuongCarlene PetesGeneve AwongSamuel DouglasDongxia LinJordan NietoFrancesco Maria GalassiRebecca BorellaLucia FidanzaMarco MattioliChiara LeoneIsabella NeriMarianna MeschiariLuca CicchettiAnna IannoneTommaso TrentiMario SartiMassimo GirardisGiovanni GuaraldiCristina MussiniFabio FacchinettiAndrea CossarizzaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sara De Biasi
Domenico Lo Tartaro
Lara Gibellini
Annamaria Paolini
Andrew Quong
Carlene Petes
Geneve Awong
Samuel Douglas
Dongxia Lin
Jordan Nieto
Francesco Maria Galassi
Rebecca Borella
Lucia Fidanza
Marco Mattioli
Chiara Leone
Isabella Neri
Marianna Meschiari
Luca Cicchetti
Anna Iannone
Tommaso Trenti
Mario Sarti
Massimo Girardis
Giovanni Guaraldi
Cristina Mussini
Fabio Facchinetti
Andrea Cossarizza
Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection
description SARS-CoV-2 infection of expecting mothers has been reported. Here the authors profile the peripheral blood from 14 pregnant women with asymptomatic or mild SARS-CoV-2 infection to find grossly normal immune cell composition but heterogenous induction of pro-inflammatory cytokines, thereby implicating possible therapeutic targets for virus-induced damages during pregnancy.
format article
author Sara De Biasi
Domenico Lo Tartaro
Lara Gibellini
Annamaria Paolini
Andrew Quong
Carlene Petes
Geneve Awong
Samuel Douglas
Dongxia Lin
Jordan Nieto
Francesco Maria Galassi
Rebecca Borella
Lucia Fidanza
Marco Mattioli
Chiara Leone
Isabella Neri
Marianna Meschiari
Luca Cicchetti
Anna Iannone
Tommaso Trenti
Mario Sarti
Massimo Girardis
Giovanni Guaraldi
Cristina Mussini
Fabio Facchinetti
Andrea Cossarizza
author_facet Sara De Biasi
Domenico Lo Tartaro
Lara Gibellini
Annamaria Paolini
Andrew Quong
Carlene Petes
Geneve Awong
Samuel Douglas
Dongxia Lin
Jordan Nieto
Francesco Maria Galassi
Rebecca Borella
Lucia Fidanza
Marco Mattioli
Chiara Leone
Isabella Neri
Marianna Meschiari
Luca Cicchetti
Anna Iannone
Tommaso Trenti
Mario Sarti
Massimo Girardis
Giovanni Guaraldi
Cristina Mussini
Fabio Facchinetti
Andrea Cossarizza
author_sort Sara De Biasi
title Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection
title_short Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection
title_full Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection
title_fullStr Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection
title_full_unstemmed Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection
title_sort endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic sars-cov-2 infection
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/a1354789176743538389b83400e3252c
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