Tracking SARS-CoV-2: Novel Trends and Diagnostic Strategies

The COVID-19 pandemic has had an enormous impact on economies and health systems globally, therefore a top priority is the development of increasingly better diagnostic and surveillance alternatives to slow down the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In order...

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Autores principales: Linda P. Guaman-Bautista, Erick Moreta-Urbano, Claudia G. Oña-Arias, Marbel Torres-Arias, Nikolaos C. Kyriakidis, Koray Malcı, Nestor Jonguitud-Borrego, Leonardo Rios-Solis, Espiridion Ramos-Martinez, Andrés López-Cortés, Carlos Barba-Ostria
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Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/a137758a1a264ff386ea7a23d16f18fc
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spelling oai:doaj.org-article:a137758a1a264ff386ea7a23d16f18fc2021-11-25T17:20:27ZTracking SARS-CoV-2: Novel Trends and Diagnostic Strategies10.3390/diagnostics111119812075-4418https://doaj.org/article/a137758a1a264ff386ea7a23d16f18fc2021-10-01T00:00:00Zhttps://www.mdpi.com/2075-4418/11/11/1981https://doaj.org/toc/2075-4418The COVID-19 pandemic has had an enormous impact on economies and health systems globally, therefore a top priority is the development of increasingly better diagnostic and surveillance alternatives to slow down the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In order to establish massive testing and contact tracing policies, it is crucial to have a clear view of the diagnostic options available and their principal advantages and drawbacks. Although classical molecular methods such as RT-qPCR are broadly used, diagnostic alternatives based on technologies such as LAMP, antigen, serological testing, or the application of novel technologies such as CRISPR-Cas for diagnostics, are also discussed. The present review also discusses the most important automation strategies employed to increase testing capability. Several serological-based diagnostic kits are presented, as well as novel nanotechnology-based diagnostic methods. In summary, this review provides a clear diagnostic landscape of the most relevant tools to track COVID-19.Linda P. Guaman-BautistaErick Moreta-UrbanoClaudia G. Oña-AriasMarbel Torres-AriasNikolaos C. KyriakidisKoray MalcıNestor Jonguitud-BorregoLeonardo Rios-SolisEspiridion Ramos-MartinezAndrés López-CortésCarlos Barba-OstriaMDPI AGarticleCOVID-19nucleic acid amplification testantigen testingCRISPR-based diagnosticsnanotechnology-based diagnosticsautomationMedicine (General)R5-920ENDiagnostics, Vol 11, Iss 1981, p 1981 (2021)
institution DOAJ
collection DOAJ
language EN
topic COVID-19
nucleic acid amplification test
antigen testing
CRISPR-based diagnostics
nanotechnology-based diagnostics
automation
Medicine (General)
R5-920
spellingShingle COVID-19
nucleic acid amplification test
antigen testing
CRISPR-based diagnostics
nanotechnology-based diagnostics
automation
Medicine (General)
R5-920
Linda P. Guaman-Bautista
Erick Moreta-Urbano
Claudia G. Oña-Arias
Marbel Torres-Arias
Nikolaos C. Kyriakidis
Koray Malcı
Nestor Jonguitud-Borrego
Leonardo Rios-Solis
Espiridion Ramos-Martinez
Andrés López-Cortés
Carlos Barba-Ostria
Tracking SARS-CoV-2: Novel Trends and Diagnostic Strategies
description The COVID-19 pandemic has had an enormous impact on economies and health systems globally, therefore a top priority is the development of increasingly better diagnostic and surveillance alternatives to slow down the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In order to establish massive testing and contact tracing policies, it is crucial to have a clear view of the diagnostic options available and their principal advantages and drawbacks. Although classical molecular methods such as RT-qPCR are broadly used, diagnostic alternatives based on technologies such as LAMP, antigen, serological testing, or the application of novel technologies such as CRISPR-Cas for diagnostics, are also discussed. The present review also discusses the most important automation strategies employed to increase testing capability. Several serological-based diagnostic kits are presented, as well as novel nanotechnology-based diagnostic methods. In summary, this review provides a clear diagnostic landscape of the most relevant tools to track COVID-19.
format article
author Linda P. Guaman-Bautista
Erick Moreta-Urbano
Claudia G. Oña-Arias
Marbel Torres-Arias
Nikolaos C. Kyriakidis
Koray Malcı
Nestor Jonguitud-Borrego
Leonardo Rios-Solis
Espiridion Ramos-Martinez
Andrés López-Cortés
Carlos Barba-Ostria
author_facet Linda P. Guaman-Bautista
Erick Moreta-Urbano
Claudia G. Oña-Arias
Marbel Torres-Arias
Nikolaos C. Kyriakidis
Koray Malcı
Nestor Jonguitud-Borrego
Leonardo Rios-Solis
Espiridion Ramos-Martinez
Andrés López-Cortés
Carlos Barba-Ostria
author_sort Linda P. Guaman-Bautista
title Tracking SARS-CoV-2: Novel Trends and Diagnostic Strategies
title_short Tracking SARS-CoV-2: Novel Trends and Diagnostic Strategies
title_full Tracking SARS-CoV-2: Novel Trends and Diagnostic Strategies
title_fullStr Tracking SARS-CoV-2: Novel Trends and Diagnostic Strategies
title_full_unstemmed Tracking SARS-CoV-2: Novel Trends and Diagnostic Strategies
title_sort tracking sars-cov-2: novel trends and diagnostic strategies
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/a137758a1a264ff386ea7a23d16f18fc
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