Tracking SARS-CoV-2: Novel Trends and Diagnostic Strategies
The COVID-19 pandemic has had an enormous impact on economies and health systems globally, therefore a top priority is the development of increasingly better diagnostic and surveillance alternatives to slow down the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In order...
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MDPI AG
2021
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oai:doaj.org-article:a137758a1a264ff386ea7a23d16f18fc2021-11-25T17:20:27ZTracking SARS-CoV-2: Novel Trends and Diagnostic Strategies10.3390/diagnostics111119812075-4418https://doaj.org/article/a137758a1a264ff386ea7a23d16f18fc2021-10-01T00:00:00Zhttps://www.mdpi.com/2075-4418/11/11/1981https://doaj.org/toc/2075-4418The COVID-19 pandemic has had an enormous impact on economies and health systems globally, therefore a top priority is the development of increasingly better diagnostic and surveillance alternatives to slow down the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In order to establish massive testing and contact tracing policies, it is crucial to have a clear view of the diagnostic options available and their principal advantages and drawbacks. Although classical molecular methods such as RT-qPCR are broadly used, diagnostic alternatives based on technologies such as LAMP, antigen, serological testing, or the application of novel technologies such as CRISPR-Cas for diagnostics, are also discussed. The present review also discusses the most important automation strategies employed to increase testing capability. Several serological-based diagnostic kits are presented, as well as novel nanotechnology-based diagnostic methods. In summary, this review provides a clear diagnostic landscape of the most relevant tools to track COVID-19.Linda P. Guaman-BautistaErick Moreta-UrbanoClaudia G. Oña-AriasMarbel Torres-AriasNikolaos C. KyriakidisKoray MalcıNestor Jonguitud-BorregoLeonardo Rios-SolisEspiridion Ramos-MartinezAndrés López-CortésCarlos Barba-OstriaMDPI AGarticleCOVID-19nucleic acid amplification testantigen testingCRISPR-based diagnosticsnanotechnology-based diagnosticsautomationMedicine (General)R5-920ENDiagnostics, Vol 11, Iss 1981, p 1981 (2021) |
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COVID-19 nucleic acid amplification test antigen testing CRISPR-based diagnostics nanotechnology-based diagnostics automation Medicine (General) R5-920 |
spellingShingle |
COVID-19 nucleic acid amplification test antigen testing CRISPR-based diagnostics nanotechnology-based diagnostics automation Medicine (General) R5-920 Linda P. Guaman-Bautista Erick Moreta-Urbano Claudia G. Oña-Arias Marbel Torres-Arias Nikolaos C. Kyriakidis Koray Malcı Nestor Jonguitud-Borrego Leonardo Rios-Solis Espiridion Ramos-Martinez Andrés López-Cortés Carlos Barba-Ostria Tracking SARS-CoV-2: Novel Trends and Diagnostic Strategies |
description |
The COVID-19 pandemic has had an enormous impact on economies and health systems globally, therefore a top priority is the development of increasingly better diagnostic and surveillance alternatives to slow down the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In order to establish massive testing and contact tracing policies, it is crucial to have a clear view of the diagnostic options available and their principal advantages and drawbacks. Although classical molecular methods such as RT-qPCR are broadly used, diagnostic alternatives based on technologies such as LAMP, antigen, serological testing, or the application of novel technologies such as CRISPR-Cas for diagnostics, are also discussed. The present review also discusses the most important automation strategies employed to increase testing capability. Several serological-based diagnostic kits are presented, as well as novel nanotechnology-based diagnostic methods. In summary, this review provides a clear diagnostic landscape of the most relevant tools to track COVID-19. |
format |
article |
author |
Linda P. Guaman-Bautista Erick Moreta-Urbano Claudia G. Oña-Arias Marbel Torres-Arias Nikolaos C. Kyriakidis Koray Malcı Nestor Jonguitud-Borrego Leonardo Rios-Solis Espiridion Ramos-Martinez Andrés López-Cortés Carlos Barba-Ostria |
author_facet |
Linda P. Guaman-Bautista Erick Moreta-Urbano Claudia G. Oña-Arias Marbel Torres-Arias Nikolaos C. Kyriakidis Koray Malcı Nestor Jonguitud-Borrego Leonardo Rios-Solis Espiridion Ramos-Martinez Andrés López-Cortés Carlos Barba-Ostria |
author_sort |
Linda P. Guaman-Bautista |
title |
Tracking SARS-CoV-2: Novel Trends and Diagnostic Strategies |
title_short |
Tracking SARS-CoV-2: Novel Trends and Diagnostic Strategies |
title_full |
Tracking SARS-CoV-2: Novel Trends and Diagnostic Strategies |
title_fullStr |
Tracking SARS-CoV-2: Novel Trends and Diagnostic Strategies |
title_full_unstemmed |
Tracking SARS-CoV-2: Novel Trends and Diagnostic Strategies |
title_sort |
tracking sars-cov-2: novel trends and diagnostic strategies |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doaj.org/article/a137758a1a264ff386ea7a23d16f18fc |
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