Long-term retinal nerve fiber layer changes following nonarteritic anterior ischemic optic neuropathy

Gad Dotan,1 Michaella Goldstein,1 Anat Kesler,1 Barry Skarf21Department of Ophthalmology, Tel Aviv Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; 2Eye Care Services, Henry Ford Hospital, Detroit, MI, USABackground: In cases of nonarteritic anterior ischemic optic...

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Autores principales:	Dotan G, Goldstein M, Kesler A, Skarf B
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/a140261e2685475e9b0220aa64255d73
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spelling	oai:doaj.org-article:a140261e2685475e9b0220aa64255d732021-12-02T05:18:17ZLong-term retinal nerve fiber layer changes following nonarteritic anterior ischemic optic neuropathy1177-54671177-5483https://doaj.org/article/a140261e2685475e9b0220aa64255d732013-04-01T00:00:00Zhttp://www.dovepress.com/long-term-retinal-nerve-fiber-layer-changes-following-nonarteritic-ant-a12800https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Gad Dotan,1 Michaella Goldstein,1 Anat Kesler,1 Barry Skarf21Department of Ophthalmology, Tel Aviv Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; 2Eye Care Services, Henry Ford Hospital, Detroit, MI, USABackground: In cases of nonarteritic anterior ischemic optic neuropathy (NAION), retinal nerve fiber layer (RNFL) thickness changes have been described during the first 12 months following the acute event. The purpose of this study was to report on the long-term RNFL changes in these eyes beyond the first year following onset of NAION.Methods: Fourteen eyes of 13 patients with NAION were analyzed in this retrospective observational case series study. Uninvolved eyes served as controls. All patients underwent a complete neuro-ophthalmological examination and repeat measurements of peripapillary RNFL thickness using Stratus optical coherence tomography.Results: On optical coherence tomography scan performed on average 6 months following onset of NAION, the mean global RNFL thickness (59.8 ± 11.8 μm) was significantly thinner (P < 0.001) compared with uninvolved eyes (95.1 ± 13.9 μm). In a second optical coherence tomography scan performed on average 13 (range 12–23) months later, the mean global RNFL thickness (58.9 ± 6.5 μm) was not significantly different (P = 0.702) from the first scan.Conclusion: There appears to be no further RNFL loss beyond the first 6 months following an acute event of NAION.Keywords: optical coherence tomography, retinal nerve fiber layer, nonartertic anterior ischemic optic neuropathyDotan GGoldstein MKesler ASkarf BDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 735-740 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Dotan G Goldstein M Kesler A Skarf B Long-term retinal nerve fiber layer changes following nonarteritic anterior ischemic optic neuropathy
description	Gad Dotan,1 Michaella Goldstein,1 Anat Kesler,1 Barry Skarf21Department of Ophthalmology, Tel Aviv Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; 2Eye Care Services, Henry Ford Hospital, Detroit, MI, USABackground: In cases of nonarteritic anterior ischemic optic neuropathy (NAION), retinal nerve fiber layer (RNFL) thickness changes have been described during the first 12 months following the acute event. The purpose of this study was to report on the long-term RNFL changes in these eyes beyond the first year following onset of NAION.Methods: Fourteen eyes of 13 patients with NAION were analyzed in this retrospective observational case series study. Uninvolved eyes served as controls. All patients underwent a complete neuro-ophthalmological examination and repeat measurements of peripapillary RNFL thickness using Stratus optical coherence tomography.Results: On optical coherence tomography scan performed on average 6 months following onset of NAION, the mean global RNFL thickness (59.8 ± 11.8 μm) was significantly thinner (P < 0.001) compared with uninvolved eyes (95.1 ± 13.9 μm). In a second optical coherence tomography scan performed on average 13 (range 12–23) months later, the mean global RNFL thickness (58.9 ± 6.5 μm) was not significantly different (P = 0.702) from the first scan.Conclusion: There appears to be no further RNFL loss beyond the first 6 months following an acute event of NAION.Keywords: optical coherence tomography, retinal nerve fiber layer, nonartertic anterior ischemic optic neuropathy
format	article
author	Dotan G Goldstein M Kesler A Skarf B
author_facet	Dotan G Goldstein M Kesler A Skarf B
author_sort	Dotan G
title	Long-term retinal nerve fiber layer changes following nonarteritic anterior ischemic optic neuropathy
title_short	Long-term retinal nerve fiber layer changes following nonarteritic anterior ischemic optic neuropathy
title_full	Long-term retinal nerve fiber layer changes following nonarteritic anterior ischemic optic neuropathy
title_fullStr	Long-term retinal nerve fiber layer changes following nonarteritic anterior ischemic optic neuropathy
title_full_unstemmed	Long-term retinal nerve fiber layer changes following nonarteritic anterior ischemic optic neuropathy
title_sort	long-term retinal nerve fiber layer changes following nonarteritic anterior ischemic optic neuropathy
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/a140261e2685475e9b0220aa64255d73
work_keys_str_mv	AT dotang longtermretinalnervefiberlayerchangesfollowingnonarteriticanteriorischemicopticneuropathy AT goldsteinm longtermretinalnervefiberlayerchangesfollowingnonarteriticanteriorischemicopticneuropathy AT keslera longtermretinalnervefiberlayerchangesfollowingnonarteriticanteriorischemicopticneuropathy AT skarfb longtermretinalnervefiberlayerchangesfollowingnonarteriticanteriorischemicopticneuropathy
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Long-term retinal nerve fiber layer changes following nonarteritic anterior ischemic optic neuropathy

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