Distinct roles for H4 and H2A.Z acetylation in RNA transcription in African trypanosomes

Histone modification and deposition are key regulators of transcription. Here, Kraus et al. provide a quantitative histone acetylome for Trypanosoma brucei, identify histone modifications enriched at transcription start sites, and show how H4 and H2A.Z acetylation affect histone deposition and trans...

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Autores principales:	Amelie J. Kraus, Jens T. Vanselow, Stephanie Lamer, Benedikt G. Brink, Andreas Schlosser, T. Nicolai Siegel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a14549f1d03c4a6187e8857e45f98178
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spelling	oai:doaj.org-article:a14549f1d03c4a6187e8857e45f981782021-12-02T17:31:09ZDistinct roles for H4 and H2A.Z acetylation in RNA transcription in African trypanosomes10.1038/s41467-020-15274-02041-1723https://doaj.org/article/a14549f1d03c4a6187e8857e45f981782020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15274-0https://doaj.org/toc/2041-1723Histone modification and deposition are key regulators of transcription. Here, Kraus et al. provide a quantitative histone acetylome for Trypanosoma brucei, identify histone modifications enriched at transcription start sites, and show how H4 and H2A.Z acetylation affect histone deposition and transcription in trypanosomes.Amelie J. KrausJens T. VanselowStephanie LamerBenedikt G. BrinkAndreas SchlosserT. Nicolai SiegelNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Amelie J. Kraus Jens T. Vanselow Stephanie Lamer Benedikt G. Brink Andreas Schlosser T. Nicolai Siegel Distinct roles for H4 and H2A.Z acetylation in RNA transcription in African trypanosomes
description	Histone modification and deposition are key regulators of transcription. Here, Kraus et al. provide a quantitative histone acetylome for Trypanosoma brucei, identify histone modifications enriched at transcription start sites, and show how H4 and H2A.Z acetylation affect histone deposition and transcription in trypanosomes.
format	article
author	Amelie J. Kraus Jens T. Vanselow Stephanie Lamer Benedikt G. Brink Andreas Schlosser T. Nicolai Siegel
author_facet	Amelie J. Kraus Jens T. Vanselow Stephanie Lamer Benedikt G. Brink Andreas Schlosser T. Nicolai Siegel
author_sort	Amelie J. Kraus
title	Distinct roles for H4 and H2A.Z acetylation in RNA transcription in African trypanosomes
title_short	Distinct roles for H4 and H2A.Z acetylation in RNA transcription in African trypanosomes
title_full	Distinct roles for H4 and H2A.Z acetylation in RNA transcription in African trypanosomes
title_fullStr	Distinct roles for H4 and H2A.Z acetylation in RNA transcription in African trypanosomes
title_full_unstemmed	Distinct roles for H4 and H2A.Z acetylation in RNA transcription in African trypanosomes
title_sort	distinct roles for h4 and h2a.z acetylation in rna transcription in african trypanosomes
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a14549f1d03c4a6187e8857e45f98178
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Distinct roles for H4 and H2A.Z acetylation in RNA transcription in African trypanosomes

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