Direct CH/CH functionalization of 1,3-dihydroxy-9H-xanthen-9-one and 1,3-dimethoxy-9H-xanthen-9-one with 1,2,4-triazines and quinazoline

An electron-deficient series of 1,2,4-triazines and quinazoline have been used for cross-dehydrogenative coupling with 1,3-dihydroxy and 1,3-dimethoxyxanthones to give stable nucleophilic addition products. The adducts and their subsequent oxidation products were obtained in good yields and the stru...

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Autores principales:	A. D. Sharapov, R. F. Fatykhov, I. A. Khalymbadzha, O. N. Chupakhin
Formato:	article
Lenguaje:	EN RU
Publicado:	Uralʹskij federalʹnyj universitet imeni pervogo Prezidenta Rossii B.N. Elʹcina 2020
Materias:	сross-dehydrogenative coupling reactions 1,2,4-triazines quinazolines xanthones Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/a151b403c8ee4d3195b39384404b3a78
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spelling	oai:doaj.org-article:a151b403c8ee4d3195b39384404b3a782021-12-01T05:53:11ZDirect CH/CH functionalization of 1,3-dihydroxy-9H-xanthen-9-one and 1,3-dimethoxy-9H-xanthen-9-one with 1,2,4-triazines and quinazoline2411-141410.15826/chimtech.2020.7.4.17https://doaj.org/article/a151b403c8ee4d3195b39384404b3a782020-12-01T00:00:00Zhttps://journals.urfu.ru/index.php/chimtech/article/view/4815https://doaj.org/toc/2411-1414An electron-deficient series of 1,2,4-triazines and quinazoline have been used for cross-dehydrogenative coupling with 1,3-dihydroxy and 1,3-dimethoxyxanthones to give stable nucleophilic addition products. The adducts and their subsequent oxidation products were obtained in good yields and the structures of the compounds were confirmed by 1H NMR spectroscopy. These results expand the scope of the methodology of nucleophilic substitution of hydrogen with the participation of xanthones with azines. Moreover, this methodology makes it possible to obtain new organic materials based on xanthones, which have a wide spectrum of biological activity.A. D. SharapovR. F. FatykhovI. A. KhalymbadzhaO. N. ChupakhinUralʹskij federalʹnyj universitet imeni pervogo Prezidenta Rossii B.N. Elʹcina articleсross-dehydrogenative coupling reactions1,2,4-triazinesquinazolinesxanthonesChemistryQD1-999ENRUChimica Techno Acta, Vol 7, Iss 4, Pp 233-236 (2020)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	сross-dehydrogenative coupling reactions 1,2,4-triazines quinazolines xanthones Chemistry QD1-999
spellingShingle	сross-dehydrogenative coupling reactions 1,2,4-triazines quinazolines xanthones Chemistry QD1-999 A. D. Sharapov R. F. Fatykhov I. A. Khalymbadzha O. N. Chupakhin Direct CH/CH functionalization of 1,3-dihydroxy-9H-xanthen-9-one and 1,3-dimethoxy-9H-xanthen-9-one with 1,2,4-triazines and quinazoline
description	An electron-deficient series of 1,2,4-triazines and quinazoline have been used for cross-dehydrogenative coupling with 1,3-dihydroxy and 1,3-dimethoxyxanthones to give stable nucleophilic addition products. The adducts and their subsequent oxidation products were obtained in good yields and the structures of the compounds were confirmed by 1H NMR spectroscopy. These results expand the scope of the methodology of nucleophilic substitution of hydrogen with the participation of xanthones with azines. Moreover, this methodology makes it possible to obtain new organic materials based on xanthones, which have a wide spectrum of biological activity.
format	article
author	A. D. Sharapov R. F. Fatykhov I. A. Khalymbadzha O. N. Chupakhin
author_facet	A. D. Sharapov R. F. Fatykhov I. A. Khalymbadzha O. N. Chupakhin
author_sort	A. D. Sharapov
title	Direct CH/CH functionalization of 1,3-dihydroxy-9H-xanthen-9-one and 1,3-dimethoxy-9H-xanthen-9-one with 1,2,4-triazines and quinazoline
title_short	Direct CH/CH functionalization of 1,3-dihydroxy-9H-xanthen-9-one and 1,3-dimethoxy-9H-xanthen-9-one with 1,2,4-triazines and quinazoline
title_full	Direct CH/CH functionalization of 1,3-dihydroxy-9H-xanthen-9-one and 1,3-dimethoxy-9H-xanthen-9-one with 1,2,4-triazines and quinazoline
title_fullStr	Direct CH/CH functionalization of 1,3-dihydroxy-9H-xanthen-9-one and 1,3-dimethoxy-9H-xanthen-9-one with 1,2,4-triazines and quinazoline
title_full_unstemmed	Direct CH/CH functionalization of 1,3-dihydroxy-9H-xanthen-9-one and 1,3-dimethoxy-9H-xanthen-9-one with 1,2,4-triazines and quinazoline
title_sort	direct ch/ch functionalization of 1,3-dihydroxy-9h-xanthen-9-one and 1,3-dimethoxy-9h-xanthen-9-one with 1,2,4-triazines and quinazoline
publisher	Uralʹskij federalʹnyj universitet imeni pervogo Prezidenta Rossii B.N. Elʹcina
publishDate	2020
url	https://doaj.org/article/a151b403c8ee4d3195b39384404b3a78
work_keys_str_mv	AT adsharapov directchchfunctionalizationof13dihydroxy9hxanthen9oneand13dimethoxy9hxanthen9onewith124triazinesandquinazoline AT rffatykhov directchchfunctionalizationof13dihydroxy9hxanthen9oneand13dimethoxy9hxanthen9onewith124triazinesandquinazoline AT iakhalymbadzha directchchfunctionalizationof13dihydroxy9hxanthen9oneand13dimethoxy9hxanthen9onewith124triazinesandquinazoline AT onchupakhin directchchfunctionalizationof13dihydroxy9hxanthen9oneand13dimethoxy9hxanthen9onewith124triazinesandquinazoline
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Direct CH/CH functionalization of 1,3-dihydroxy-9H-xanthen-9-one and 1,3-dimethoxy-9H-xanthen-9-one with 1,2,4-triazines and quinazoline

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