Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion

Previous studies have used fluorescently labelled cells to demonstrate the incorporation of transplanted photoreceptor precursors into the mouse retina. Here, the authors show that fluorescent proteins are passed between the host and transplanted cells rather than migration of donor cells into the r...

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Autores principales: Mandeep S. Singh, Jasmin Balmer, Alun R. Barnard, Sher A. Aslam, Daniela Moralli, Catherine M. Green, Alona Barnea-Cramer, Isabel Duncan, Robert E. MacLaren
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/a152f0eaffda4bcba6ad872e86359ba3
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spelling oai:doaj.org-article:a152f0eaffda4bcba6ad872e86359ba32021-12-02T17:32:22ZTransplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion10.1038/ncomms135372041-1723https://doaj.org/article/a152f0eaffda4bcba6ad872e86359ba32016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13537https://doaj.org/toc/2041-1723Previous studies have used fluorescently labelled cells to demonstrate the incorporation of transplanted photoreceptor precursors into the mouse retina. Here, the authors show that fluorescent proteins are passed between the host and transplanted cells rather than migration of donor cells into the retina.Mandeep S. SinghJasmin BalmerAlun R. BarnardSher A. AslamDaniela MoralliCatherine M. GreenAlona Barnea-CramerIsabel DuncanRobert E. MacLarenNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-5 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Mandeep S. Singh
Jasmin Balmer
Alun R. Barnard
Sher A. Aslam
Daniela Moralli
Catherine M. Green
Alona Barnea-Cramer
Isabel Duncan
Robert E. MacLaren
Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
description Previous studies have used fluorescently labelled cells to demonstrate the incorporation of transplanted photoreceptor precursors into the mouse retina. Here, the authors show that fluorescent proteins are passed between the host and transplanted cells rather than migration of donor cells into the retina.
format article
author Mandeep S. Singh
Jasmin Balmer
Alun R. Barnard
Sher A. Aslam
Daniela Moralli
Catherine M. Green
Alona Barnea-Cramer
Isabel Duncan
Robert E. MacLaren
author_facet Mandeep S. Singh
Jasmin Balmer
Alun R. Barnard
Sher A. Aslam
Daniela Moralli
Catherine M. Green
Alona Barnea-Cramer
Isabel Duncan
Robert E. MacLaren
author_sort Mandeep S. Singh
title Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
title_short Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
title_full Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
title_fullStr Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
title_full_unstemmed Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
title_sort transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/a152f0eaffda4bcba6ad872e86359ba3
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