Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly

Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly

Low complexity (LC) domains can drive the formation of both amyloid fibrils and protein droplets. Here, the authors identify reversible amyloid cores from the LC of hnRNPA1, based on which they elucidate the structural basis of reversible fibrillation and its interplay with hnRNPA1 droplet formation...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Xinrui Gui, Feng Luo, Yichen Li, Heng Zhou, Zhenheng Qin, Zhenying Liu, Jinge Gu, Muyun Xie, Kun Zhao, Bin Dai, Woo Shik Shin, Jianhua He, Lin He, Lin Jiang, Minglei Zhao, Bo Sun, Xueming Li, Cong Liu, Dan Li
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/a160475f7cbf47d1b2ddb73a38f8b907
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Internet

https://doaj.org/article/a160475f7cbf47d1b2ddb73a38f8b907

Documents similaires