Structural and functional implication of RAP80 ΔGlu81 mutation.

Receptor Associated Protein 80 (RAP80) is a member of RAP80-BRCA1-CCDC98 complex family and helps in its recruitment to the DNA damage site for effective homologous recombination repair. It encompasses two tandem UIMs (UIM1 and UIM2) motif at its N-terminus, which interact with K-63 linked polyubiqu...

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Autores principales: Vikrant, Rajan Kumar, Lumbini R Yadav, Pallavi Nakhwa, Sanjeev K Waghmare, Peyush Goyal, Ashok K Varma
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/a16b3b7723584d8f874ae92fca9099a9
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