Automatic structure-based NMR methyl resonance assignment in large proteins

The structures and dynamics of large proteins can be studied with methyl-based NMR but peak assignment is still challenging. Here the authors present MethylFLYA that allows automated assignment of methyl groups and apply it to five proteins with molecular weights in the range from 28 to 358 kDa.

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Bibliographic Details
Main Authors: Iva Pritišanac, Julia M. Würz, T. Reid Alderson, Peter Güntert
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Q
Online Access:https://doaj.org/article/a1784461fd9c43e19b12737b3b10db75
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