Genome-wide systematic identification of methyltransferase recognition and modification patterns

Single molecule real-time DNA sequencing allows genome-wide identification of DNA methylation patterns. Here, Jensen et al. present a high-throughput method that allows rapid coupling of DNA methylation patterns with their corresponding methyltransferase genes in bacteria.

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Autores principales: Torbjørn Ølshøj Jensen, Christian Tellgren-Roth, Stephanie Redl, Jérôme Maury, Simo Abdessamad Baallal Jacobsen, Lasse Ebdrup Pedersen, Alex Toftgaard Nielsen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/a17958eda3f1464098a0d1f520c422e1
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Sumario:Single molecule real-time DNA sequencing allows genome-wide identification of DNA methylation patterns. Here, Jensen et al. present a high-throughput method that allows rapid coupling of DNA methylation patterns with their corresponding methyltransferase genes in bacteria.