Host Pathways Important for <named-content content-type="genus-species">Coxiella burnetii</named-content> Infection Revealed by Genome-Wide RNA Interference Screening

Host Pathways Important for <named-content content-type="genus-species">Coxiella burnetii</named-content> Infection Revealed by Genome-Wide RNA Interference Screening

ABSTRACT Coxiella burnetii is an intracellular pathogen that replicates within a lysosome-like vacuole. A Dot/Icm type IVB secretion system is used by C. burnetii to translocate effector proteins into the host cytosol that likely modulate host factor function. To identify host determinants required...

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Bibliographic Details
Main Authors: Justin A. McDonough, Hayley J. Newton, Scott Klum, Rachel Swiss, Hervé Agaisse, Craig R. Roy
Format: article
Language:EN
Published: American Society for Microbiology 2013
Subjects:
Microbiology
QR1-502
Online Access:https://doaj.org/article/a179843a94dc4a3b9faff6d6e6760f39
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