Meckelin 3 is necessary for photoreceptor outer segment development in rat Meckel syndrome.

Meckelin 3 is necessary for photoreceptor outer segment development in rat Meckel syndrome.

Ciliopathies lead to multiorgan pathologies that include renal cysts, deafness, obesity and retinal degeneration. Retinal photoreceptors have connecting cilia joining the inner and outer segment that are responsible for transport of molecules to develop and maintain the outer segment process. The pr...

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Autores principales: Sarika Tiwari, Scott Hudson, Vincent H Gattone, Caroline Miller, Ellen A G Chernoff, Teri L Belecky-Adams
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/a17b55a7275e4518b9b114d376fc4e30
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