Human brain dynamics in active spatial navigation

Abstract Spatial navigation is a complex cognitive process based on multiple senses that are integrated and processed by a wide network of brain areas. Previous studies have revealed the retrosplenial complex (RSC) to be modulated in a task-related manner during navigation. However, these studies re...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Tien-Thong Nguyen Do, Chin-Teng Lin, Klaus Gramann
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a17bdf49c91d468aa291a52fa23d6584
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:a17bdf49c91d468aa291a52fa23d6584
record_format	dspace
spelling	oai:doaj.org-article:a17bdf49c91d468aa291a52fa23d65842021-12-02T17:14:24ZHuman brain dynamics in active spatial navigation10.1038/s41598-021-92246-42045-2322https://doaj.org/article/a17bdf49c91d468aa291a52fa23d65842021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-92246-4https://doaj.org/toc/2045-2322Abstract Spatial navigation is a complex cognitive process based on multiple senses that are integrated and processed by a wide network of brain areas. Previous studies have revealed the retrosplenial complex (RSC) to be modulated in a task-related manner during navigation. However, these studies restricted participants’ movement to stationary setups, which might have impacted heading computations due to the absence of vestibular and proprioceptive inputs. Here, we present evidence of human RSC theta oscillation (4–8 Hz) in an active spatial navigation task where participants actively ambulated from one location to several other points while the position of a landmark and the starting location were updated. The results revealed theta power in the RSC to be pronounced during heading changes but not during translational movements, indicating that physical rotations induce human RSC theta activity. This finding provides a potential evidence of head-direction computation in RSC in healthy humans during active spatial navigation.Tien-Thong Nguyen DoChin-Teng LinKlaus GramannNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Tien-Thong Nguyen Do Chin-Teng Lin Klaus Gramann Human brain dynamics in active spatial navigation
description	Abstract Spatial navigation is a complex cognitive process based on multiple senses that are integrated and processed by a wide network of brain areas. Previous studies have revealed the retrosplenial complex (RSC) to be modulated in a task-related manner during navigation. However, these studies restricted participants’ movement to stationary setups, which might have impacted heading computations due to the absence of vestibular and proprioceptive inputs. Here, we present evidence of human RSC theta oscillation (4–8 Hz) in an active spatial navigation task where participants actively ambulated from one location to several other points while the position of a landmark and the starting location were updated. The results revealed theta power in the RSC to be pronounced during heading changes but not during translational movements, indicating that physical rotations induce human RSC theta activity. This finding provides a potential evidence of head-direction computation in RSC in healthy humans during active spatial navigation.
format	article
author	Tien-Thong Nguyen Do Chin-Teng Lin Klaus Gramann
author_facet	Tien-Thong Nguyen Do Chin-Teng Lin Klaus Gramann
author_sort	Tien-Thong Nguyen Do
title	Human brain dynamics in active spatial navigation
title_short	Human brain dynamics in active spatial navigation
title_full	Human brain dynamics in active spatial navigation
title_fullStr	Human brain dynamics in active spatial navigation
title_full_unstemmed	Human brain dynamics in active spatial navigation
title_sort	human brain dynamics in active spatial navigation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a17bdf49c91d468aa291a52fa23d6584
work_keys_str_mv	AT tienthongnguyendo humanbraindynamicsinactivespatialnavigation AT chintenglin humanbraindynamicsinactivespatialnavigation AT klausgramann humanbraindynamicsinactivespatialnavigation
_version_	1718381335744086016

Human brain dynamics in active spatial navigation

Ejemplares similares