A randomized clinical trial testing the anti-inflammatory effects of preemptive inhaled nitric oxide in human liver transplantation.

A randomized clinical trial testing the anti-inflammatory effects of preemptive inhaled nitric oxide in human liver transplantation.

Decreases in endothelial nitric oxide synthase derived nitric oxide (NO) production during liver transplantation promotes injury. We hypothesized that preemptive inhaled NO (iNO) would improve allograft function (primary) and reduce complications post-transplantation (secondary). Patients at two uni...

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Autores principales: John D Lang, Alvin B Smith, Angela Brandon, Kelley M Bradley, Yuliang Liu, Wei Li, D Ralph Crowe, Nirag C Jhala, Richard C Cross, Luc Frenette, Kenneth Martay, Youri L Vater, Alexander A Vitin, Gregory A Dembo, Derek A Dubay, J Steven Bynon, Jeff M Szychowski, Jorge D Reyes, Jeffrey B Halldorson, Stephen C Rayhill, Andre A Dick, Ramasamy Bakthavatsalam, Jared Brandenberger, Jo Ann Broeckel-Elrod, Laura Sissons-Ross, Terry Jordan, Lucinda Y Chen, Arunotai Siriussawakul, Devin E Eckhoff, Rakesh P Patel
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/a1804e87351e4177a82c6305bacd9369
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