The Features of Pathobiology and Clinical translation of Approved treatments for Coronavirus Disease 2019 (COVID-19)

Background: The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is currently the most important etiological agent of acute respiratory distress syndrome (ARDS) with millions of infections and deaths in the last two years worldwide. Several reasons and parameters are responsible for the...

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Autores principales:	Ali Fallah, Hadi Razavi Nikoo, Hamidreza Abbasi, Azadeh Mohammad-Hasani, Abasalt Hosseinzadeh Colagar, Ayyoob Khosravi
Formato:	article
Lenguaje:	EN
Publicado:	Karger Publishers 2021
Materias:	Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/a1826a191a3840abad6601fde8088d9f
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spelling	oai:doaj.org-article:a1826a191a3840abad6601fde8088d9f2021-11-25T07:47:19ZThe Features of Pathobiology and Clinical translation of Approved treatments for Coronavirus Disease 2019 (COVID-19)0300-55261423-010010.1159/000520234https://doaj.org/article/a1826a191a3840abad6601fde8088d9f2021-10-01T00:00:00Zhttps://www.karger.com/Article/FullText/520234https://doaj.org/toc/0300-5526https://doaj.org/toc/1423-0100Background: The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is currently the most important etiological agent of acute respiratory distress syndrome (ARDS) with millions of infections and deaths in the last two years worldwide. Several reasons and parameters are responsible for the difficult management of coronavirus disease-2019 (COVID-19) patients; the first is virus behavioral factors such as high transmission rate, and the different molecular and cellular mechanisms of pathogenesis remain a matter of controversy, is another factor. Summary: In the present review, we attempted to explain about features of SARS-COV-2, particularly focusing on the various aspects of pathogenesis and treatment strategies. Key Messages: We note evidence for the understanding of the precise molecular and cellular mechanisms of SARS-CoV-2 pathogenesis, which can help design the appropriate drug or vaccine. Additionally, and importantly, we reported the updated issues associated with the history and development of treatment strategies such as, drugs, vaccines, and other medications that have been approved or under consideration in clinics and markets worldwide.Ali FallahHadi Razavi NikooHamidreza AbbasiAzadeh Mohammad-HasaniAbasalt Hosseinzadeh ColagarAyyoob KhosraviKarger PublishersarticleSpecialties of internal medicineRC581-951ENIntervirology (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Specialties of internal medicine RC581-951
spellingShingle	Specialties of internal medicine RC581-951 Ali Fallah Hadi Razavi Nikoo Hamidreza Abbasi Azadeh Mohammad-Hasani Abasalt Hosseinzadeh Colagar Ayyoob Khosravi The Features of Pathobiology and Clinical translation of Approved treatments for Coronavirus Disease 2019 (COVID-19)
description	Background: The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is currently the most important etiological agent of acute respiratory distress syndrome (ARDS) with millions of infections and deaths in the last two years worldwide. Several reasons and parameters are responsible for the difficult management of coronavirus disease-2019 (COVID-19) patients; the first is virus behavioral factors such as high transmission rate, and the different molecular and cellular mechanisms of pathogenesis remain a matter of controversy, is another factor. Summary: In the present review, we attempted to explain about features of SARS-COV-2, particularly focusing on the various aspects of pathogenesis and treatment strategies. Key Messages: We note evidence for the understanding of the precise molecular and cellular mechanisms of SARS-CoV-2 pathogenesis, which can help design the appropriate drug or vaccine. Additionally, and importantly, we reported the updated issues associated with the history and development of treatment strategies such as, drugs, vaccines, and other medications that have been approved or under consideration in clinics and markets worldwide.
format	article
author	Ali Fallah Hadi Razavi Nikoo Hamidreza Abbasi Azadeh Mohammad-Hasani Abasalt Hosseinzadeh Colagar Ayyoob Khosravi
author_facet	Ali Fallah Hadi Razavi Nikoo Hamidreza Abbasi Azadeh Mohammad-Hasani Abasalt Hosseinzadeh Colagar Ayyoob Khosravi
author_sort	Ali Fallah
title	The Features of Pathobiology and Clinical translation of Approved treatments for Coronavirus Disease 2019 (COVID-19)
title_short	The Features of Pathobiology and Clinical translation of Approved treatments for Coronavirus Disease 2019 (COVID-19)
title_full	The Features of Pathobiology and Clinical translation of Approved treatments for Coronavirus Disease 2019 (COVID-19)
title_fullStr	The Features of Pathobiology and Clinical translation of Approved treatments for Coronavirus Disease 2019 (COVID-19)
title_full_unstemmed	The Features of Pathobiology and Clinical translation of Approved treatments for Coronavirus Disease 2019 (COVID-19)
title_sort	features of pathobiology and clinical translation of approved treatments for coronavirus disease 2019 (covid-19)
publisher	Karger Publishers
publishDate	2021
url	https://doaj.org/article/a1826a191a3840abad6601fde8088d9f
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The Features of Pathobiology and Clinical translation of Approved treatments for Coronavirus Disease 2019 (COVID-19)

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