Abnormal RNA stability in amyotrophic lateral sclerosis

Abnormal RNA stability in amyotrophic lateral sclerosis

RNA instability may be a contributing factor in amyotrophic lateral sclerosis (ALS). Here the authors carry out genome-wide assessment of RNA synthesis and stability in cells derived from patients with C9orf72 ALS, sporadic ALS and healthy controls.

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Detalles Bibliográficos
Autores principales: E. M. Tank, C. Figueroa-Romero, L. M. Hinder, K. Bedi, H. C. Archbold, X. Li, K. Weskamp, N. Safren, X. Paez-Colasante, C. Pacut, S. Thumma, M. T. Paulsen, K. Guo, J. Hur, M. Ljungman, E. L. Feldman, S. J. Barmada
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/a184e2bde9db4d10910de0c58efe84b6
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Sumario:RNA instability may be a contributing factor in amyotrophic lateral sclerosis (ALS). Here the authors carry out genome-wide assessment of RNA synthesis and stability in cells derived from patients with C9orf72 ALS, sporadic ALS and healthy controls.

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