Abnormal RNA stability in amyotrophic lateral sclerosis
RNA instability may be a contributing factor in amyotrophic lateral sclerosis (ALS). Here the authors carry out genome-wide assessment of RNA synthesis and stability in cells derived from patients with C9orf72 ALS, sporadic ALS and healthy controls.
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Nature Portfolio
2018
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oai:doaj.org-article:a184e2bde9db4d10910de0c58efe84b62021-12-02T16:56:59ZAbnormal RNA stability in amyotrophic lateral sclerosis10.1038/s41467-018-05049-z2041-1723https://doaj.org/article/a184e2bde9db4d10910de0c58efe84b62018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05049-zhttps://doaj.org/toc/2041-1723RNA instability may be a contributing factor in amyotrophic lateral sclerosis (ALS). Here the authors carry out genome-wide assessment of RNA synthesis and stability in cells derived from patients with C9orf72 ALS, sporadic ALS and healthy controls.E. M. TankC. Figueroa-RomeroL. M. HinderK. BediH. C. ArchboldX. LiK. WeskampN. SafrenX. Paez-ColasanteC. PacutS. ThummaM. T. PaulsenK. GuoJ. HurM. LjungmanE. L. FeldmanS. J. BarmadaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018) |
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Science Q E. M. Tank C. Figueroa-Romero L. M. Hinder K. Bedi H. C. Archbold X. Li K. Weskamp N. Safren X. Paez-Colasante C. Pacut S. Thumma M. T. Paulsen K. Guo J. Hur M. Ljungman E. L. Feldman S. J. Barmada Abnormal RNA stability in amyotrophic lateral sclerosis |
description |
RNA instability may be a contributing factor in amyotrophic lateral sclerosis (ALS). Here the authors carry out genome-wide assessment of RNA synthesis and stability in cells derived from patients with C9orf72 ALS, sporadic ALS and healthy controls. |
format |
article |
author |
E. M. Tank C. Figueroa-Romero L. M. Hinder K. Bedi H. C. Archbold X. Li K. Weskamp N. Safren X. Paez-Colasante C. Pacut S. Thumma M. T. Paulsen K. Guo J. Hur M. Ljungman E. L. Feldman S. J. Barmada |
author_facet |
E. M. Tank C. Figueroa-Romero L. M. Hinder K. Bedi H. C. Archbold X. Li K. Weskamp N. Safren X. Paez-Colasante C. Pacut S. Thumma M. T. Paulsen K. Guo J. Hur M. Ljungman E. L. Feldman S. J. Barmada |
author_sort |
E. M. Tank |
title |
Abnormal RNA stability in amyotrophic lateral sclerosis |
title_short |
Abnormal RNA stability in amyotrophic lateral sclerosis |
title_full |
Abnormal RNA stability in amyotrophic lateral sclerosis |
title_fullStr |
Abnormal RNA stability in amyotrophic lateral sclerosis |
title_full_unstemmed |
Abnormal RNA stability in amyotrophic lateral sclerosis |
title_sort |
abnormal rna stability in amyotrophic lateral sclerosis |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/a184e2bde9db4d10910de0c58efe84b6 |
work_keys_str_mv |
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_version_ |
1718382697893593088 |