Abnormal RNA stability in amyotrophic lateral sclerosis

Abnormal RNA stability in amyotrophic lateral sclerosis

RNA instability may be a contributing factor in amyotrophic lateral sclerosis (ALS). Here the authors carry out genome-wide assessment of RNA synthesis and stability in cells derived from patients with C9orf72 ALS, sporadic ALS and healthy controls.

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Auteurs principaux: E. M. Tank, C. Figueroa-Romero, L. M. Hinder, K. Bedi, H. C. Archbold, X. Li, K. Weskamp, N. Safren, X. Paez-Colasante, C. Pacut, S. Thumma, M. T. Paulsen, K. Guo, J. Hur, M. Ljungman, E. L. Feldman, S. J. Barmada
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/a184e2bde9db4d10910de0c58efe84b6
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spelling oai:doaj.org-article:a184e2bde9db4d10910de0c58efe84b62021-12-02T16:56:59ZAbnormal RNA stability in amyotrophic lateral sclerosis10.1038/s41467-018-05049-z2041-1723https://doaj.org/article/a184e2bde9db4d10910de0c58efe84b62018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05049-zhttps://doaj.org/toc/2041-1723RNA instability may be a contributing factor in amyotrophic lateral sclerosis (ALS). Here the authors carry out genome-wide assessment of RNA synthesis and stability in cells derived from patients with C9orf72 ALS, sporadic ALS and healthy controls.E. M. TankC. Figueroa-RomeroL. M. HinderK. BediH. C. ArchboldX. LiK. WeskampN. SafrenX. Paez-ColasanteC. PacutS. ThummaM. T. PaulsenK. GuoJ. HurM. LjungmanE. L. FeldmanS. J. BarmadaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
E. M. Tank
C. Figueroa-Romero
L. M. Hinder
K. Bedi
H. C. Archbold
X. Li
K. Weskamp
N. Safren
X. Paez-Colasante
C. Pacut
S. Thumma
M. T. Paulsen
K. Guo
J. Hur
M. Ljungman
E. L. Feldman
S. J. Barmada
Abnormal RNA stability in amyotrophic lateral sclerosis
description RNA instability may be a contributing factor in amyotrophic lateral sclerosis (ALS). Here the authors carry out genome-wide assessment of RNA synthesis and stability in cells derived from patients with C9orf72 ALS, sporadic ALS and healthy controls.
format article
author E. M. Tank
C. Figueroa-Romero
L. M. Hinder
K. Bedi
H. C. Archbold
X. Li
K. Weskamp
N. Safren
X. Paez-Colasante
C. Pacut
S. Thumma
M. T. Paulsen
K. Guo
J. Hur
M. Ljungman
E. L. Feldman
S. J. Barmada
author_facet E. M. Tank
C. Figueroa-Romero
L. M. Hinder
K. Bedi
H. C. Archbold
X. Li
K. Weskamp
N. Safren
X. Paez-Colasante
C. Pacut
S. Thumma
M. T. Paulsen
K. Guo
J. Hur
M. Ljungman
E. L. Feldman
S. J. Barmada
author_sort E. M. Tank
title Abnormal RNA stability in amyotrophic lateral sclerosis
title_short Abnormal RNA stability in amyotrophic lateral sclerosis
title_full Abnormal RNA stability in amyotrophic lateral sclerosis
title_fullStr Abnormal RNA stability in amyotrophic lateral sclerosis
title_full_unstemmed Abnormal RNA stability in amyotrophic lateral sclerosis
title_sort abnormal rna stability in amyotrophic lateral sclerosis
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/a184e2bde9db4d10910de0c58efe84b6
work_keys_str_mv AT emtank abnormalrnastabilityinamyotrophiclateralsclerosis
AT cfigueroaromero abnormalrnastabilityinamyotrophiclateralsclerosis
AT lmhinder abnormalrnastabilityinamyotrophiclateralsclerosis
AT kbedi abnormalrnastabilityinamyotrophiclateralsclerosis
AT hcarchbold abnormalrnastabilityinamyotrophiclateralsclerosis
AT xli abnormalrnastabilityinamyotrophiclateralsclerosis
AT kweskamp abnormalrnastabilityinamyotrophiclateralsclerosis
AT nsafren abnormalrnastabilityinamyotrophiclateralsclerosis
AT xpaezcolasante abnormalrnastabilityinamyotrophiclateralsclerosis
AT cpacut abnormalrnastabilityinamyotrophiclateralsclerosis
AT sthumma abnormalrnastabilityinamyotrophiclateralsclerosis
AT mtpaulsen abnormalrnastabilityinamyotrophiclateralsclerosis
AT kguo abnormalrnastabilityinamyotrophiclateralsclerosis
AT jhur abnormalrnastabilityinamyotrophiclateralsclerosis
AT mljungman abnormalrnastabilityinamyotrophiclateralsclerosis
AT elfeldman abnormalrnastabilityinamyotrophiclateralsclerosis
AT sjbarmada abnormalrnastabilityinamyotrophiclateralsclerosis
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