Medical comorbidities in Saudi patients with narcolepsy: a case-control study
Objective: This case-control study sought to assess comorbid medical disorders in patients with narcolepsy type-1 (NT-1) and type-2 (NT-2). Material and Methods: he study comprised 80 consecutive Arab (Saudi) patients with narcolepsy (NT-1=56 and NT-2=24) and a control group of 211 adults m...
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Brazilian Association of Sleep and Latin American Federation of Sleep Societies
2021
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oai:doaj.org-article:a1946eafd33c4168ac26285298b6449c2021-11-24T12:26:11ZMedical comorbidities in Saudi patients with narcolepsy: a case-control study1984-06591984-0063001410.5935/1984-0063.20200070https://doaj.org/article/a1946eafd33c4168ac26285298b6449c2021-10-01T00:00:00Zhttps://www.sleepscience.org.br/details/2826/en-US/medical-comorbidities-in-saudi-patients-with-narcolepsy--a-case-control-studyhttps://doaj.org/toc/1984-0659https://doaj.org/toc/1984-0063Objective: This case-control study sought to assess comorbid medical disorders in patients with narcolepsy type-1 (NT-1) and type-2 (NT-2). Material and Methods: he study comprised 80 consecutive Arab (Saudi) patients with narcolepsy (NT-1=56 and NT-2=24) and a control group of 211 adults matched for age, sex, and body mass index (BMI). Data were collected from cases and controls based on a predesigned questionnaire that was formulated based on previous studies to evaluate the chosen medical comorbidities. Results: Narcolepsy patients had a higher prevalence of hypothyroidism and hyperlipidemia and a higher prevalence of high-risk for OSA than controls. Hyperlipidemia was more common in cases than controls, 8 (10%) vs. 3 (1.4%), p=0.002. After adjusting for age, sex, and BMI, the odds-ratios for hypothyroidism and high risk for OSA in the NT-1 group was 5.49 (95% CI, [0.8 - 38.6]) and 69.99 ((95%CI [20.6 -237.4]), respectively, and in the NT-2 group, 12.5, 95%CI [1.6-97.7], and 33.3, 95%CI [8.2-135.7], respectively. Conclusion: Arab (Saudi) narcolepsy patients had a higher association with hypothyroidism, hyperlipidemia, and a higher risk of OSA than controls.Ahmed Salem BaHammamAwad H OlaishMajid Al-OmarAljohara S AlmeneessierBrazilian Association of Sleep and Latin American Federation of Sleep Societies articlehypertensionsleepdiabetes mellitusdisorders of excessive somnolencehyperlipidemiashypothyroidismPsychologyBF1-990Consciousness. CognitionBF309-499ENSleep Science, Vol 14, Iss 3, Pp 286-290 (2021) |
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hypertension sleep diabetes mellitus disorders of excessive somnolence hyperlipidemias hypothyroidism Psychology BF1-990 Consciousness. Cognition BF309-499 |
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hypertension sleep diabetes mellitus disorders of excessive somnolence hyperlipidemias hypothyroidism Psychology BF1-990 Consciousness. Cognition BF309-499 Ahmed Salem BaHammam Awad H Olaish Majid Al-Omar Aljohara S Almeneessier Medical comorbidities in Saudi patients with narcolepsy: a case-control study |
description |
Objective: This case-control study sought to assess comorbid medical disorders in patients with narcolepsy type-1 (NT-1) and type-2 (NT-2).
Material and Methods: he study comprised 80 consecutive Arab (Saudi) patients with narcolepsy (NT-1=56 and NT-2=24) and a control group of 211 adults matched for age, sex, and body mass index (BMI). Data were collected from cases and controls based on a predesigned questionnaire that was formulated based on previous studies to evaluate the chosen medical comorbidities.
Results: Narcolepsy patients had a higher prevalence of hypothyroidism and hyperlipidemia and a higher prevalence of high-risk for OSA than controls. Hyperlipidemia was more common in cases than controls, 8 (10%) vs. 3 (1.4%), p=0.002. After adjusting for age, sex, and BMI, the odds-ratios for hypothyroidism and high risk for OSA in the NT-1 group was 5.49 (95% CI, [0.8 - 38.6]) and 69.99 ((95%CI [20.6 -237.4]), respectively, and in the NT-2 group, 12.5, 95%CI [1.6-97.7], and 33.3, 95%CI [8.2-135.7], respectively.
Conclusion: Arab (Saudi) narcolepsy patients had a higher association with hypothyroidism, hyperlipidemia, and a higher risk of OSA than controls. |
format |
article |
author |
Ahmed Salem BaHammam Awad H Olaish Majid Al-Omar Aljohara S Almeneessier |
author_facet |
Ahmed Salem BaHammam Awad H Olaish Majid Al-Omar Aljohara S Almeneessier |
author_sort |
Ahmed Salem BaHammam |
title |
Medical comorbidities in Saudi patients with narcolepsy: a case-control study |
title_short |
Medical comorbidities in Saudi patients with narcolepsy: a case-control study |
title_full |
Medical comorbidities in Saudi patients with narcolepsy: a case-control study |
title_fullStr |
Medical comorbidities in Saudi patients with narcolepsy: a case-control study |
title_full_unstemmed |
Medical comorbidities in Saudi patients with narcolepsy: a case-control study |
title_sort |
medical comorbidities in saudi patients with narcolepsy: a case-control study |
publisher |
Brazilian Association of Sleep and Latin American Federation of Sleep Societies |
publishDate |
2021 |
url |
https://doaj.org/article/a1946eafd33c4168ac26285298b6449c |
work_keys_str_mv |
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