Medical comorbidities in Saudi patients with narcolepsy: a case-control study

Objective: This case-control study sought to assess comorbid medical disorders in patients with narcolepsy type-1 (NT-1) and type-2 (NT-2). Material and Methods: he study comprised 80 consecutive Arab (Saudi) patients with narcolepsy (NT-1=56 and NT-2=24) and a control group of 211 adults m...

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Autores principales: Ahmed Salem BaHammam, Awad H Olaish, Majid Al-Omar, Aljohara S Almeneessier
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Lenguaje:EN
Publicado: Brazilian Association of Sleep and Latin American Federation of Sleep Societies 2021
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Acceso en línea:https://doaj.org/article/a1946eafd33c4168ac26285298b6449c
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spelling oai:doaj.org-article:a1946eafd33c4168ac26285298b6449c2021-11-24T12:26:11ZMedical comorbidities in Saudi patients with narcolepsy: a case-control study1984-06591984-0063001410.5935/1984-0063.20200070https://doaj.org/article/a1946eafd33c4168ac26285298b6449c2021-10-01T00:00:00Zhttps://www.sleepscience.org.br/details/2826/en-US/medical-comorbidities-in-saudi-patients-with-narcolepsy--a-case-control-studyhttps://doaj.org/toc/1984-0659https://doaj.org/toc/1984-0063Objective: This case-control study sought to assess comorbid medical disorders in patients with narcolepsy type-1 (NT-1) and type-2 (NT-2). Material and Methods: he study comprised 80 consecutive Arab (Saudi) patients with narcolepsy (NT-1=56 and NT-2=24) and a control group of 211 adults matched for age, sex, and body mass index (BMI). Data were collected from cases and controls based on a predesigned questionnaire that was formulated based on previous studies to evaluate the chosen medical comorbidities. Results: Narcolepsy patients had a higher prevalence of hypothyroidism and hyperlipidemia and a higher prevalence of high-risk for OSA than controls. Hyperlipidemia was more common in cases than controls, 8 (10%) vs. 3 (1.4%), p=0.002. After adjusting for age, sex, and BMI, the odds-ratios for hypothyroidism and high risk for OSA in the NT-1 group was 5.49 (95% CI, [0.8 - 38.6]) and 69.99 ((95%CI [20.6 -237.4]), respectively, and in the NT-2 group, 12.5, 95%CI [1.6-97.7], and 33.3, 95%CI [8.2-135.7], respectively. Conclusion: Arab (Saudi) narcolepsy patients had a higher association with hypothyroidism, hyperlipidemia, and a higher risk of OSA than controls.Ahmed Salem BaHammamAwad H OlaishMajid Al-OmarAljohara S AlmeneessierBrazilian Association of Sleep and Latin American Federation of Sleep Societies articlehypertensionsleepdiabetes mellitusdisorders of excessive somnolencehyperlipidemiashypothyroidismPsychologyBF1-990Consciousness. CognitionBF309-499ENSleep Science, Vol 14, Iss 3, Pp 286-290 (2021)
institution DOAJ
collection DOAJ
language EN
topic hypertension
sleep
diabetes mellitus
disorders of excessive somnolence
hyperlipidemias
hypothyroidism
Psychology
BF1-990
Consciousness. Cognition
BF309-499
spellingShingle hypertension
sleep
diabetes mellitus
disorders of excessive somnolence
hyperlipidemias
hypothyroidism
Psychology
BF1-990
Consciousness. Cognition
BF309-499
Ahmed Salem BaHammam
Awad H Olaish
Majid Al-Omar
Aljohara S Almeneessier
Medical comorbidities in Saudi patients with narcolepsy: a case-control study
description Objective: This case-control study sought to assess comorbid medical disorders in patients with narcolepsy type-1 (NT-1) and type-2 (NT-2). Material and Methods: he study comprised 80 consecutive Arab (Saudi) patients with narcolepsy (NT-1=56 and NT-2=24) and a control group of 211 adults matched for age, sex, and body mass index (BMI). Data were collected from cases and controls based on a predesigned questionnaire that was formulated based on previous studies to evaluate the chosen medical comorbidities. Results: Narcolepsy patients had a higher prevalence of hypothyroidism and hyperlipidemia and a higher prevalence of high-risk for OSA than controls. Hyperlipidemia was more common in cases than controls, 8 (10%) vs. 3 (1.4%), p=0.002. After adjusting for age, sex, and BMI, the odds-ratios for hypothyroidism and high risk for OSA in the NT-1 group was 5.49 (95% CI, [0.8 - 38.6]) and 69.99 ((95%CI [20.6 -237.4]), respectively, and in the NT-2 group, 12.5, 95%CI [1.6-97.7], and 33.3, 95%CI [8.2-135.7], respectively. Conclusion: Arab (Saudi) narcolepsy patients had a higher association with hypothyroidism, hyperlipidemia, and a higher risk of OSA than controls.
format article
author Ahmed Salem BaHammam
Awad H Olaish
Majid Al-Omar
Aljohara S Almeneessier
author_facet Ahmed Salem BaHammam
Awad H Olaish
Majid Al-Omar
Aljohara S Almeneessier
author_sort Ahmed Salem BaHammam
title Medical comorbidities in Saudi patients with narcolepsy: a case-control study
title_short Medical comorbidities in Saudi patients with narcolepsy: a case-control study
title_full Medical comorbidities in Saudi patients with narcolepsy: a case-control study
title_fullStr Medical comorbidities in Saudi patients with narcolepsy: a case-control study
title_full_unstemmed Medical comorbidities in Saudi patients with narcolepsy: a case-control study
title_sort medical comorbidities in saudi patients with narcolepsy: a case-control study
publisher Brazilian Association of Sleep and Latin American Federation of Sleep Societies
publishDate 2021
url https://doaj.org/article/a1946eafd33c4168ac26285298b6449c
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