A universal dual mechanism immunotherapy for the treatment of influenza virus infections

In this study, the authors combine an anti-viral drug and immune system inducer to treat influenza A and B viral infections in vitro and in vivo. They show that the compound outperforms zanamivir alone as it is still able to clear infection three days post infection, and it can be administered via d...

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Autores principales:	Xin Liu, Boning Zhang, Yingcai Wang, Hanan S. Haymour, Fenghua Zhang, Le-cun Xu, Madduri Srinivasarao, Philip S. Low
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a1a9abde9412466fa5e7117a4ffece35
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spelling	oai:doaj.org-article:a1a9abde9412466fa5e7117a4ffece352021-12-02T16:56:51ZA universal dual mechanism immunotherapy for the treatment of influenza virus infections10.1038/s41467-020-19386-52041-1723https://doaj.org/article/a1a9abde9412466fa5e7117a4ffece352020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19386-5https://doaj.org/toc/2041-1723In this study, the authors combine an anti-viral drug and immune system inducer to treat influenza A and B viral infections in vitro and in vivo. They show that the compound outperforms zanamivir alone as it is still able to clear infection three days post infection, and it can be administered via different routes without reduced efficacy.Xin LiuBoning ZhangYingcai WangHanan S. HaymourFenghua ZhangLe-cun XuMadduri SrinivasaraoPhilip S. LowNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xin Liu Boning Zhang Yingcai Wang Hanan S. Haymour Fenghua Zhang Le-cun Xu Madduri Srinivasarao Philip S. Low A universal dual mechanism immunotherapy for the treatment of influenza virus infections
description	In this study, the authors combine an anti-viral drug and immune system inducer to treat influenza A and B viral infections in vitro and in vivo. They show that the compound outperforms zanamivir alone as it is still able to clear infection three days post infection, and it can be administered via different routes without reduced efficacy.
format	article
author	Xin Liu Boning Zhang Yingcai Wang Hanan S. Haymour Fenghua Zhang Le-cun Xu Madduri Srinivasarao Philip S. Low
author_facet	Xin Liu Boning Zhang Yingcai Wang Hanan S. Haymour Fenghua Zhang Le-cun Xu Madduri Srinivasarao Philip S. Low
author_sort	Xin Liu
title	A universal dual mechanism immunotherapy for the treatment of influenza virus infections
title_short	A universal dual mechanism immunotherapy for the treatment of influenza virus infections
title_full	A universal dual mechanism immunotherapy for the treatment of influenza virus infections
title_fullStr	A universal dual mechanism immunotherapy for the treatment of influenza virus infections
title_full_unstemmed	A universal dual mechanism immunotherapy for the treatment of influenza virus infections
title_sort	universal dual mechanism immunotherapy for the treatment of influenza virus infections
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/a1a9abde9412466fa5e7117a4ffece35
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A universal dual mechanism immunotherapy for the treatment of influenza virus infections

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