A gammaherpesvirus complement regulatory protein promotes initiation of infection by activation of protein kinase Akt/PKB.
<h4>Background</h4>Viruses have evolved to evade the host's complement system. The open reading frames 4 (ORF4) of gammaherpesviruses encode homologs of regulators of complement activation (RCA) proteins, which inhibit complement activation at the level of C3 and C4 deposition. Besi...
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Autores principales: | Beatrix Steer, Barbara Adler, Stipan Jonjic, James P Stewart, Heiko Adler |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
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Materias: | |
Acceso en línea: | https://doaj.org/article/a1acac407f004e75b28c4940117bd50d |
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