A gammaherpesvirus complement regulatory protein promotes initiation of infection by activation of protein kinase Akt/PKB.
<h4>Background</h4>Viruses have evolved to evade the host's complement system. The open reading frames 4 (ORF4) of gammaherpesviruses encode homologs of regulators of complement activation (RCA) proteins, which inhibit complement activation at the level of C3 and C4 deposition. Besi...
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Main Authors: | , , , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2010
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Subjects: | |
Online Access: | https://doaj.org/article/a1acac407f004e75b28c4940117bd50d |
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