Association between statin medication and hearing impairment in a national health screening cohort

Abstract This study aimed to investigate the association of previous stain use with hearing impairment in an adult population. Data from the ≥ 40-year-old population in the Korean National Health Insurance Service Health Screening Cohort were used. The hearing impairment group was classified based o...

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Autores principales:	So Young Kim, Chang Ho Lee, Chanyang Min, Dae Myoung Yoo, Hyo Geun Choi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a1b0791467d54a448d49592fb6582ffd
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spelling	oai:doaj.org-article:a1b0791467d54a448d49592fb6582ffd2021-12-02T18:30:40ZAssociation between statin medication and hearing impairment in a national health screening cohort10.1038/s41598-021-93916-z2045-2322https://doaj.org/article/a1b0791467d54a448d49592fb6582ffd2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-93916-zhttps://doaj.org/toc/2045-2322Abstract This study aimed to investigate the association of previous stain use with hearing impairment in an adult population. Data from the ≥ 40-year-old population in the Korean National Health Insurance Service Health Screening Cohort were used. The hearing impairment group was classified based on the national registry of hearing-impaired persons. Control participants were randomly selected and matched for age, sex, income, and region of residence. The number of days of statin prescription during the 2 years before the diagnosis of hearing impairment was compared between the hearing impairment group and the control group using conditional logistic regression analysis. Additional analyses were conducted according to age and sex. The number of days of previous statin use was not different between the hearing impairment group and the control group (adjusted odds ratio [aOR] = 0.94, 95% confidence interval (CI) = 0.86–1.02, P = 0.118). According to age, in the ≥ 70-year-old group, those with hearing impairment had 11% lower rates of previous statin use than those in the control group (aOR = 0.89, 95% CI = 0.80–0.99, P = 0.039). According to sex, in the male group, 12% lower rates of previous statin use were observed among those with hearing impairment than among those in the control group (aOR = 0.88, 95% CI = 0.79–0.99, P = 0.037). Previous statin use might have an effect on reducing the prevalence of hearing impairment in elderly individuals and men.So Young KimChang Ho LeeChanyang MinDae Myoung YooHyo Geun ChoiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q So Young Kim Chang Ho Lee Chanyang Min Dae Myoung Yoo Hyo Geun Choi Association between statin medication and hearing impairment in a national health screening cohort
description	Abstract This study aimed to investigate the association of previous stain use with hearing impairment in an adult population. Data from the ≥ 40-year-old population in the Korean National Health Insurance Service Health Screening Cohort were used. The hearing impairment group was classified based on the national registry of hearing-impaired persons. Control participants were randomly selected and matched for age, sex, income, and region of residence. The number of days of statin prescription during the 2 years before the diagnosis of hearing impairment was compared between the hearing impairment group and the control group using conditional logistic regression analysis. Additional analyses were conducted according to age and sex. The number of days of previous statin use was not different between the hearing impairment group and the control group (adjusted odds ratio [aOR] = 0.94, 95% confidence interval (CI) = 0.86–1.02, P = 0.118). According to age, in the ≥ 70-year-old group, those with hearing impairment had 11% lower rates of previous statin use than those in the control group (aOR = 0.89, 95% CI = 0.80–0.99, P = 0.039). According to sex, in the male group, 12% lower rates of previous statin use were observed among those with hearing impairment than among those in the control group (aOR = 0.88, 95% CI = 0.79–0.99, P = 0.037). Previous statin use might have an effect on reducing the prevalence of hearing impairment in elderly individuals and men.
format	article
author	So Young Kim Chang Ho Lee Chanyang Min Dae Myoung Yoo Hyo Geun Choi
author_facet	So Young Kim Chang Ho Lee Chanyang Min Dae Myoung Yoo Hyo Geun Choi
author_sort	So Young Kim
title	Association between statin medication and hearing impairment in a national health screening cohort
title_short	Association between statin medication and hearing impairment in a national health screening cohort
title_full	Association between statin medication and hearing impairment in a national health screening cohort
title_fullStr	Association between statin medication and hearing impairment in a national health screening cohort
title_full_unstemmed	Association between statin medication and hearing impairment in a national health screening cohort
title_sort	association between statin medication and hearing impairment in a national health screening cohort
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a1b0791467d54a448d49592fb6582ffd
work_keys_str_mv	AT soyoungkim associationbetweenstatinmedicationandhearingimpairmentinanationalhealthscreeningcohort AT changholee associationbetweenstatinmedicationandhearingimpairmentinanationalhealthscreeningcohort AT chanyangmin associationbetweenstatinmedicationandhearingimpairmentinanationalhealthscreeningcohort AT daemyoungyoo associationbetweenstatinmedicationandhearingimpairmentinanationalhealthscreeningcohort AT hyogeunchoi associationbetweenstatinmedicationandhearingimpairmentinanationalhealthscreeningcohort
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Association between statin medication and hearing impairment in a national health screening cohort

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