Programmed cell removal by calreticulin in tissue homeostasis and cancer

Macrophage-mediated programmed cell removal (PrCR) allows clearance of living cells. Here the authors show that, in mouse models, activated macrophages create an “eat me” signal via calreticulin secretion on neutrophils during peritonitis and on cancer cells, determining in both cases clearance by P...

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Autores principales:	Mingye Feng, Kristopher D. Marjon, Fangfang Zhu, Rachel Weissman-Tsukamoto, Aaron Levett, Katie Sullivan, Kevin S. Kao, Maxim Markovic, Paul A. Bump, Hannah M. Jackson, Timothy S. Choi, Jing Chen, Allison M. Banuelos, Jie Liu, Phung Gip, Lei Cheng, Denong Wang, Irving L. Weissman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/a1b68cf0ddc143208c23a7ee9e16b82a
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spelling	oai:doaj.org-article:a1b68cf0ddc143208c23a7ee9e16b82a2021-12-02T17:32:00ZProgrammed cell removal by calreticulin in tissue homeostasis and cancer10.1038/s41467-018-05211-72041-1723https://doaj.org/article/a1b68cf0ddc143208c23a7ee9e16b82a2018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05211-7https://doaj.org/toc/2041-1723Macrophage-mediated programmed cell removal (PrCR) allows clearance of living cells. Here the authors show that, in mouse models, activated macrophages create an “eat me” signal via calreticulin secretion on neutrophils during peritonitis and on cancer cells, determining in both cases clearance by PrCR.Mingye FengKristopher D. MarjonFangfang ZhuRachel Weissman-TsukamotoAaron LevettKatie SullivanKevin S. KaoMaxim MarkovicPaul A. BumpHannah M. JacksonTimothy S. ChoiJing ChenAllison M. BanuelosJie LiuPhung GipLei ChengDenong WangIrving L. WeissmanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mingye Feng Kristopher D. Marjon Fangfang Zhu Rachel Weissman-Tsukamoto Aaron Levett Katie Sullivan Kevin S. Kao Maxim Markovic Paul A. Bump Hannah M. Jackson Timothy S. Choi Jing Chen Allison M. Banuelos Jie Liu Phung Gip Lei Cheng Denong Wang Irving L. Weissman Programmed cell removal by calreticulin in tissue homeostasis and cancer
description	Macrophage-mediated programmed cell removal (PrCR) allows clearance of living cells. Here the authors show that, in mouse models, activated macrophages create an “eat me” signal via calreticulin secretion on neutrophils during peritonitis and on cancer cells, determining in both cases clearance by PrCR.
format	article
author	Mingye Feng Kristopher D. Marjon Fangfang Zhu Rachel Weissman-Tsukamoto Aaron Levett Katie Sullivan Kevin S. Kao Maxim Markovic Paul A. Bump Hannah M. Jackson Timothy S. Choi Jing Chen Allison M. Banuelos Jie Liu Phung Gip Lei Cheng Denong Wang Irving L. Weissman
author_facet	Mingye Feng Kristopher D. Marjon Fangfang Zhu Rachel Weissman-Tsukamoto Aaron Levett Katie Sullivan Kevin S. Kao Maxim Markovic Paul A. Bump Hannah M. Jackson Timothy S. Choi Jing Chen Allison M. Banuelos Jie Liu Phung Gip Lei Cheng Denong Wang Irving L. Weissman
author_sort	Mingye Feng
title	Programmed cell removal by calreticulin in tissue homeostasis and cancer
title_short	Programmed cell removal by calreticulin in tissue homeostasis and cancer
title_full	Programmed cell removal by calreticulin in tissue homeostasis and cancer
title_fullStr	Programmed cell removal by calreticulin in tissue homeostasis and cancer
title_full_unstemmed	Programmed cell removal by calreticulin in tissue homeostasis and cancer
title_sort	programmed cell removal by calreticulin in tissue homeostasis and cancer
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/a1b68cf0ddc143208c23a7ee9e16b82a
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Programmed cell removal by calreticulin in tissue homeostasis and cancer

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