Etiological Profile of Acute Onset Hemiparesis in Children Admitted at a Tertiary Care Teaching Hospital of Northern India

Introduction: Acute hemiparesis, weakness of either half of the body is a common nonspecific neurological response of the central nervous system to a varying of infective/non-infective aetiologies noted among admitted children. There is a paucity of data on etiologies of this condition, from this pa...

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Autores principales:	Animesh Saxena, Chandra Kanta, Sciddhartha Koonwar, Sanjeev Verma, Anit Parihar
Formato:	article
Lenguaje:	EN
Publicado:	Light House Polyclinic Mangalore 2021
Materias:	infectious etiology pediatric stroke hemiplegia northern india Medicine R
Acceso en línea:	https://doaj.org/article/a1be437a6897496aa603665d765721c0
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spelling	oai:doaj.org-article:a1be437a6897496aa603665d765721c02021-11-12T08:15:05ZEtiological Profile of Acute Onset Hemiparesis in Children Admitted at a Tertiary Care Teaching Hospital of Northern India0972-5997https://doaj.org/article/a1be437a6897496aa603665d765721c02021-10-01T00:00:00Zhttps://www.ojhas.org/issue79/2021-3-8.htmlhttps://doaj.org/toc/0972-5997Introduction: Acute hemiparesis, weakness of either half of the body is a common nonspecific neurological response of the central nervous system to a varying of infective/non-infective aetiologies noted among admitted children. There is a paucity of data on etiologies of this condition, from this part of the Indian subcontinent, so this study was planned to describe the etiological profile of hemiparesis in children. Method: This prospective observational study was done from September 2017 to August 2018 at a tertiary care teaching hospital in northern India. Consecutive children of age 2 months to 14 years, admitted with acute onset hemiparesis or developed hemiparesis during hospital stay were enrolled in the study. Data was collected in a predesigned proforma after obtaining consent. Results: 65 children (57% male) who were admitted with hemiparesis, were enrolled. The mean age at presentation was 5.7 ± 3.5 years. Central nervous system infection (CNS) was the most common cause (69%) followed by pediatric stroke (19%). Intracranial space-occupying lesions (SOL), cerebral palsy, and acute disseminated meningoencephalitis (ADEM) were the other important causes of hemiparesis. Among CNS infections, acute encephalitis was found in 43% and tuberculous meningitis in 26% of patients. Japanese encephalitis 9.2%, inflammatory granuloma & abscess (5%), chikungunya (1.5%) and rickettsial infections (1.5%) were other CNS infections identified. In 12 cases of pediatric stroke, 9 were ischemic infarct and the rest were hemorrhagic. Among ischemic infarction 3 were with the prothrombotic state each 1 case of protein C, S & antithrombin III deficiency. 3 children were comorbid with heart diseases (2 cases of valvular heart disease with infective endocarditis & one case of tetralogy of Fallot). Conclusion: This study shows that, in Uttar Pradesh, India, CNS infection and pediatric stroke (non-infective) are the most common cause of acute onset hemiparesis in children.Animesh SaxenaChandra KantaSciddhartha KoonwarSanjeev VermaAnit PariharLight House Polyclinic Mangalore articleinfectious etiologypediatric strokehemiplegianorthern indiaMedicineRENOnline Journal of Health & Allied Sciences, Vol 20, Iss 3 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	infectious etiology pediatric stroke hemiplegia northern india Medicine R
spellingShingle	infectious etiology pediatric stroke hemiplegia northern india Medicine R Animesh Saxena Chandra Kanta Sciddhartha Koonwar Sanjeev Verma Anit Parihar Etiological Profile of Acute Onset Hemiparesis in Children Admitted at a Tertiary Care Teaching Hospital of Northern India
description	Introduction: Acute hemiparesis, weakness of either half of the body is a common nonspecific neurological response of the central nervous system to a varying of infective/non-infective aetiologies noted among admitted children. There is a paucity of data on etiologies of this condition, from this part of the Indian subcontinent, so this study was planned to describe the etiological profile of hemiparesis in children. Method: This prospective observational study was done from September 2017 to August 2018 at a tertiary care teaching hospital in northern India. Consecutive children of age 2 months to 14 years, admitted with acute onset hemiparesis or developed hemiparesis during hospital stay were enrolled in the study. Data was collected in a predesigned proforma after obtaining consent. Results: 65 children (57% male) who were admitted with hemiparesis, were enrolled. The mean age at presentation was 5.7 ± 3.5 years. Central nervous system infection (CNS) was the most common cause (69%) followed by pediatric stroke (19%). Intracranial space-occupying lesions (SOL), cerebral palsy, and acute disseminated meningoencephalitis (ADEM) were the other important causes of hemiparesis. Among CNS infections, acute encephalitis was found in 43% and tuberculous meningitis in 26% of patients. Japanese encephalitis 9.2%, inflammatory granuloma & abscess (5%), chikungunya (1.5%) and rickettsial infections (1.5%) were other CNS infections identified. In 12 cases of pediatric stroke, 9 were ischemic infarct and the rest were hemorrhagic. Among ischemic infarction 3 were with the prothrombotic state each 1 case of protein C, S & antithrombin III deficiency. 3 children were comorbid with heart diseases (2 cases of valvular heart disease with infective endocarditis & one case of tetralogy of Fallot). Conclusion: This study shows that, in Uttar Pradesh, India, CNS infection and pediatric stroke (non-infective) are the most common cause of acute onset hemiparesis in children.
format	article
author	Animesh Saxena Chandra Kanta Sciddhartha Koonwar Sanjeev Verma Anit Parihar
author_facet	Animesh Saxena Chandra Kanta Sciddhartha Koonwar Sanjeev Verma Anit Parihar
author_sort	Animesh Saxena
title	Etiological Profile of Acute Onset Hemiparesis in Children Admitted at a Tertiary Care Teaching Hospital of Northern India
title_short	Etiological Profile of Acute Onset Hemiparesis in Children Admitted at a Tertiary Care Teaching Hospital of Northern India
title_full	Etiological Profile of Acute Onset Hemiparesis in Children Admitted at a Tertiary Care Teaching Hospital of Northern India
title_fullStr	Etiological Profile of Acute Onset Hemiparesis in Children Admitted at a Tertiary Care Teaching Hospital of Northern India
title_full_unstemmed	Etiological Profile of Acute Onset Hemiparesis in Children Admitted at a Tertiary Care Teaching Hospital of Northern India
title_sort	etiological profile of acute onset hemiparesis in children admitted at a tertiary care teaching hospital of northern india
publisher	Light House Polyclinic Mangalore
publishDate	2021
url	https://doaj.org/article/a1be437a6897496aa603665d765721c0
work_keys_str_mv	AT animeshsaxena etiologicalprofileofacuteonsethemiparesisinchildrenadmittedatatertiarycareteachinghospitalofnorthernindia AT chandrakanta etiologicalprofileofacuteonsethemiparesisinchildrenadmittedatatertiarycareteachinghospitalofnorthernindia AT sciddharthakoonwar etiologicalprofileofacuteonsethemiparesisinchildrenadmittedatatertiarycareteachinghospitalofnorthernindia AT sanjeevverma etiologicalprofileofacuteonsethemiparesisinchildrenadmittedatatertiarycareteachinghospitalofnorthernindia AT anitparihar etiologicalprofileofacuteonsethemiparesisinchildrenadmittedatatertiarycareteachinghospitalofnorthernindia
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Etiological Profile of Acute Onset Hemiparesis in Children Admitted at a Tertiary Care Teaching Hospital of Northern India

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