Quantifying absolute addressability in DNA origami with molecular resolution

Self-assembled DNA nanostructures hold potential as nanomachines or platforms for organized chemical synthesis, but methods for assembly quality control are lacking. Here the authors use DNA-PAINT to quantify the incorporation and accessibility of individual strands in a DNA origami platform with mo...

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Autores principales: Maximilian T. Strauss, Florian Schueder, Daniel Haas, Philipp C. Nickels, Ralf Jungmann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/a1c5267526ba4bc1bb373ab1a9f3d7a4
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Sumario:Self-assembled DNA nanostructures hold potential as nanomachines or platforms for organized chemical synthesis, but methods for assembly quality control are lacking. Here the authors use DNA-PAINT to quantify the incorporation and accessibility of individual strands in a DNA origami platform with molecular resolution.