Folic acid fortification of double fortified salt

Abstract The addition of folic acid to Double Fortified Salt (with iron and iodine) aims to simultaneously ameliorate three major micronutrient deficiencies in vulnerable populations. To make Triple Fortified Salt, we added folic acid to the iodine solution (first method) and the iron premix (second...

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Autores principales:	Oluwasegun Modupe, Juveria Siddiqui, Akhila Jonnalagadda, Levente L. Diosady
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a1c969046f2f4171b01410dd8bd98c7b
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spelling	oai:doaj.org-article:a1c969046f2f4171b01410dd8bd98c7b2021-12-02T16:08:06ZFolic acid fortification of double fortified salt10.1038/s41598-021-93194-92045-2322https://doaj.org/article/a1c969046f2f4171b01410dd8bd98c7b2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-93194-9https://doaj.org/toc/2045-2322Abstract The addition of folic acid to Double Fortified Salt (with iron and iodine) aims to simultaneously ameliorate three major micronutrient deficiencies in vulnerable populations. To make Triple Fortified Salt, we added folic acid to the iodine solution (first method) and the iron premix (second method) that are used to fortify salt with iron and iodine. When added through the solution, sodium carbonate was needed to dissolve folic acid and to adjust pH. Alternately, folic acid was added either to the iron core or sandwiched between the core and TiO2 layer of the iron premix. Folic acid and iodine were stable in all cases, retaining more than 70% of the added micronutrients after six months at 45 °C/60–70% relative hu. Adding folic acid to the premix's iron core is preferred as folic acid retention was slightly higher, and the added folic acid did not impact the salt's colour. The additional cost for adding the micronutrients to salt is about 27¢/person per year. Folic acid in the fortified salt made with the preferred method was stable in cooking and did not affect selected cooked foods' sensory properties. The technology is a cost-effective approach for simultaneously combating iron, iodine, and folic acid deficiencies.Oluwasegun ModupeJuveria SiddiquiAkhila JonnalagaddaLevente L. DiosadyNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Oluwasegun Modupe Juveria Siddiqui Akhila Jonnalagadda Levente L. Diosady Folic acid fortification of double fortified salt
description	Abstract The addition of folic acid to Double Fortified Salt (with iron and iodine) aims to simultaneously ameliorate three major micronutrient deficiencies in vulnerable populations. To make Triple Fortified Salt, we added folic acid to the iodine solution (first method) and the iron premix (second method) that are used to fortify salt with iron and iodine. When added through the solution, sodium carbonate was needed to dissolve folic acid and to adjust pH. Alternately, folic acid was added either to the iron core or sandwiched between the core and TiO2 layer of the iron premix. Folic acid and iodine were stable in all cases, retaining more than 70% of the added micronutrients after six months at 45 °C/60–70% relative hu. Adding folic acid to the premix's iron core is preferred as folic acid retention was slightly higher, and the added folic acid did not impact the salt's colour. The additional cost for adding the micronutrients to salt is about 27¢/person per year. Folic acid in the fortified salt made with the preferred method was stable in cooking and did not affect selected cooked foods' sensory properties. The technology is a cost-effective approach for simultaneously combating iron, iodine, and folic acid deficiencies.
format	article
author	Oluwasegun Modupe Juveria Siddiqui Akhila Jonnalagadda Levente L. Diosady
author_facet	Oluwasegun Modupe Juveria Siddiqui Akhila Jonnalagadda Levente L. Diosady
author_sort	Oluwasegun Modupe
title	Folic acid fortification of double fortified salt
title_short	Folic acid fortification of double fortified salt
title_full	Folic acid fortification of double fortified salt
title_fullStr	Folic acid fortification of double fortified salt
title_full_unstemmed	Folic acid fortification of double fortified salt
title_sort	folic acid fortification of double fortified salt
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a1c969046f2f4171b01410dd8bd98c7b
work_keys_str_mv	AT oluwasegunmodupe folicacidfortificationofdoublefortifiedsalt AT juveriasiddiqui folicacidfortificationofdoublefortifiedsalt AT akhilajonnalagadda folicacidfortificationofdoublefortifiedsalt AT leventeldiosady folicacidfortificationofdoublefortifiedsalt
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Folic acid fortification of double fortified salt

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