The pathophysiology of bile acid diarrhoea: differences in the colonic microbiome, metabolome and bile acids

The pathophysiology of bile acid diarrhoea: differences in the colonic microbiome, metabolome and bile acids

Abstract Bile acid diarrhoea (BAD) is a common disorder resulting from increased loss of bile acids (BAs), overlapping irritable bowel syndrome with diarrhoea (IBS-D). The gut microbiota metabolises primary BAs to secondary BAs, with differing impacts on metabolism and homeostasis. The aim of this s...

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Main Authors: Nidhi M. Sagar, Henri Duboc, Gemma L. Kay, Mohammad T. Alam, Alfian N. Wicaksono, James A. Covington, Christopher Quince, Margarita Kokkorou, Vaios Svolos, Lola J. Palmieri, Konstantinos Gerasimidis, Julian R. F. Walters, Ramesh P. Arasaradnam
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/a1cfc811b99244d6a20d7c655bd6cd31
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https://doaj.org/article/a1cfc811b99244d6a20d7c655bd6cd31

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