Impact of nutritional index on contrast-associated acute kidney injury and mortality after percutaneous coronary intervention

Abstract The risk of malnutrition in acute kidney injury and mortality in coronary artery disease patients has not been studied. This study aimed to evaluate whether nutritional status assessed by Onodera’s prognostic nutritional index (PNI) was related to percutaneous coronary intervention (PCI) ou...

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Autores principales:	Miyeun Han, Hye Won Lee, Han Cheol Lee, Hyo Jin Kim, Eun Young Seong, Sang Heon Song
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/a1d3bb9801a6416d808bc655fac7ea34
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spelling	oai:doaj.org-article:a1d3bb9801a6416d808bc655fac7ea342021-12-02T13:26:50ZImpact of nutritional index on contrast-associated acute kidney injury and mortality after percutaneous coronary intervention10.1038/s41598-021-86680-72045-2322https://doaj.org/article/a1d3bb9801a6416d808bc655fac7ea342021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-86680-7https://doaj.org/toc/2045-2322Abstract The risk of malnutrition in acute kidney injury and mortality in coronary artery disease patients has not been studied. This study aimed to evaluate whether nutritional status assessed by Onodera’s prognostic nutritional index (PNI) was related to percutaneous coronary intervention (PCI) outcomes. A total of 3731 patients who received PCI between January 2010 and December 2018 were included. The relationship between PNI at the time of PCI and the occurrence of contrast-associated acute kidney injury (AKI) and all-cause death was evaluated using logistic regression and Cox proportional hazards models, respectively. AKI occurred in 271 patients (7.3%). A low PNI was independently associated with an increased risk of AKI on multivariate logistic regression analysis (OR 0.96, 95% CI 0.94–0.98, P = 0.001). During the median follow-up of 4.3 years, Kaplan–Meier analysis showed that patients with AKI/low PNI < 47.8 had a higher death rate. After adjusting for various risk factors, a low PNI was a significant risk factor for mortality (HR 0.98, CI 0.96–0.99, P = 0.003). A low level of PNI was associated with increased mortality, especially in the group aged over 70 years and female sex. PNI was closely associated with acute kidney outcomes and patient mortality after PCI.Miyeun HanHye Won LeeHan Cheol LeeHyo Jin KimEun Young SeongSang Heon SongNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Miyeun Han Hye Won Lee Han Cheol Lee Hyo Jin Kim Eun Young Seong Sang Heon Song Impact of nutritional index on contrast-associated acute kidney injury and mortality after percutaneous coronary intervention
description	Abstract The risk of malnutrition in acute kidney injury and mortality in coronary artery disease patients has not been studied. This study aimed to evaluate whether nutritional status assessed by Onodera’s prognostic nutritional index (PNI) was related to percutaneous coronary intervention (PCI) outcomes. A total of 3731 patients who received PCI between January 2010 and December 2018 were included. The relationship between PNI at the time of PCI and the occurrence of contrast-associated acute kidney injury (AKI) and all-cause death was evaluated using logistic regression and Cox proportional hazards models, respectively. AKI occurred in 271 patients (7.3%). A low PNI was independently associated with an increased risk of AKI on multivariate logistic regression analysis (OR 0.96, 95% CI 0.94–0.98, P = 0.001). During the median follow-up of 4.3 years, Kaplan–Meier analysis showed that patients with AKI/low PNI < 47.8 had a higher death rate. After adjusting for various risk factors, a low PNI was a significant risk factor for mortality (HR 0.98, CI 0.96–0.99, P = 0.003). A low level of PNI was associated with increased mortality, especially in the group aged over 70 years and female sex. PNI was closely associated with acute kidney outcomes and patient mortality after PCI.
format	article
author	Miyeun Han Hye Won Lee Han Cheol Lee Hyo Jin Kim Eun Young Seong Sang Heon Song
author_facet	Miyeun Han Hye Won Lee Han Cheol Lee Hyo Jin Kim Eun Young Seong Sang Heon Song
author_sort	Miyeun Han
title	Impact of nutritional index on contrast-associated acute kidney injury and mortality after percutaneous coronary intervention
title_short	Impact of nutritional index on contrast-associated acute kidney injury and mortality after percutaneous coronary intervention
title_full	Impact of nutritional index on contrast-associated acute kidney injury and mortality after percutaneous coronary intervention
title_fullStr	Impact of nutritional index on contrast-associated acute kidney injury and mortality after percutaneous coronary intervention
title_full_unstemmed	Impact of nutritional index on contrast-associated acute kidney injury and mortality after percutaneous coronary intervention
title_sort	impact of nutritional index on contrast-associated acute kidney injury and mortality after percutaneous coronary intervention
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/a1d3bb9801a6416d808bc655fac7ea34
work_keys_str_mv	AT miyeunhan impactofnutritionalindexoncontrastassociatedacutekidneyinjuryandmortalityafterpercutaneouscoronaryintervention AT hyewonlee impactofnutritionalindexoncontrastassociatedacutekidneyinjuryandmortalityafterpercutaneouscoronaryintervention AT hancheollee impactofnutritionalindexoncontrastassociatedacutekidneyinjuryandmortalityafterpercutaneouscoronaryintervention AT hyojinkim impactofnutritionalindexoncontrastassociatedacutekidneyinjuryandmortalityafterpercutaneouscoronaryintervention AT eunyoungseong impactofnutritionalindexoncontrastassociatedacutekidneyinjuryandmortalityafterpercutaneouscoronaryintervention AT sangheonsong impactofnutritionalindexoncontrastassociatedacutekidneyinjuryandmortalityafterpercutaneouscoronaryintervention
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Impact of nutritional index on contrast-associated acute kidney injury and mortality after percutaneous coronary intervention

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