The CHD6 chromatin remodeler is an oxidative DNA damage response factor

Oxidative DNA damage is associated with nucleosome respacing and transcriptional changes requiring chromatin remodeling enzymes. Here, the authors reveal that the CHD6 remodeler is a DNA damage response factor that relocates to damaged sites and promotes cell survival following oxidative damage.

Guardado en:
Detalles Bibliográficos
Autores principales: Shaun Moore, N. Daniel Berger, Martijn S. Luijsterburg, Cortt G. Piett, Fintan K. T. Stanley, Christoph U. Schräder, Shujuan Fang, Jennifer A. Chan, David C. Schriemer, Zachary D. Nagel, Haico van Attikum, Aaron A. Goodarzi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/a1d6db47cd974c2ebdb72cd40605819e
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:a1d6db47cd974c2ebdb72cd40605819e
record_format dspace
spelling oai:doaj.org-article:a1d6db47cd974c2ebdb72cd40605819e2021-12-02T17:02:14ZThe CHD6 chromatin remodeler is an oxidative DNA damage response factor10.1038/s41467-018-08111-y2041-1723https://doaj.org/article/a1d6db47cd974c2ebdb72cd40605819e2019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08111-yhttps://doaj.org/toc/2041-1723Oxidative DNA damage is associated with nucleosome respacing and transcriptional changes requiring chromatin remodeling enzymes. Here, the authors reveal that the CHD6 remodeler is a DNA damage response factor that relocates to damaged sites and promotes cell survival following oxidative damage.Shaun MooreN. Daniel BergerMartijn S. LuijsterburgCortt G. PiettFintan K. T. StanleyChristoph U. SchräderShujuan FangJennifer A. ChanDavid C. SchriemerZachary D. NagelHaico van AttikumAaron A. GoodarziNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shaun Moore
N. Daniel Berger
Martijn S. Luijsterburg
Cortt G. Piett
Fintan K. T. Stanley
Christoph U. Schräder
Shujuan Fang
Jennifer A. Chan
David C. Schriemer
Zachary D. Nagel
Haico van Attikum
Aaron A. Goodarzi
The CHD6 chromatin remodeler is an oxidative DNA damage response factor
description Oxidative DNA damage is associated with nucleosome respacing and transcriptional changes requiring chromatin remodeling enzymes. Here, the authors reveal that the CHD6 remodeler is a DNA damage response factor that relocates to damaged sites and promotes cell survival following oxidative damage.
format article
author Shaun Moore
N. Daniel Berger
Martijn S. Luijsterburg
Cortt G. Piett
Fintan K. T. Stanley
Christoph U. Schräder
Shujuan Fang
Jennifer A. Chan
David C. Schriemer
Zachary D. Nagel
Haico van Attikum
Aaron A. Goodarzi
author_facet Shaun Moore
N. Daniel Berger
Martijn S. Luijsterburg
Cortt G. Piett
Fintan K. T. Stanley
Christoph U. Schräder
Shujuan Fang
Jennifer A. Chan
David C. Schriemer
Zachary D. Nagel
Haico van Attikum
Aaron A. Goodarzi
author_sort Shaun Moore
title The CHD6 chromatin remodeler is an oxidative DNA damage response factor
title_short The CHD6 chromatin remodeler is an oxidative DNA damage response factor
title_full The CHD6 chromatin remodeler is an oxidative DNA damage response factor
title_fullStr The CHD6 chromatin remodeler is an oxidative DNA damage response factor
title_full_unstemmed The CHD6 chromatin remodeler is an oxidative DNA damage response factor
title_sort chd6 chromatin remodeler is an oxidative dna damage response factor
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/a1d6db47cd974c2ebdb72cd40605819e
work_keys_str_mv AT shaunmoore thechd6chromatinremodelerisanoxidativednadamageresponsefactor
AT ndanielberger thechd6chromatinremodelerisanoxidativednadamageresponsefactor
AT martijnsluijsterburg thechd6chromatinremodelerisanoxidativednadamageresponsefactor
AT corttgpiett thechd6chromatinremodelerisanoxidativednadamageresponsefactor
AT fintanktstanley thechd6chromatinremodelerisanoxidativednadamageresponsefactor
AT christophuschrader thechd6chromatinremodelerisanoxidativednadamageresponsefactor
AT shujuanfang thechd6chromatinremodelerisanoxidativednadamageresponsefactor
AT jenniferachan thechd6chromatinremodelerisanoxidativednadamageresponsefactor
AT davidcschriemer thechd6chromatinremodelerisanoxidativednadamageresponsefactor
AT zacharydnagel thechd6chromatinremodelerisanoxidativednadamageresponsefactor
AT haicovanattikum thechd6chromatinremodelerisanoxidativednadamageresponsefactor
AT aaronagoodarzi thechd6chromatinremodelerisanoxidativednadamageresponsefactor
AT shaunmoore chd6chromatinremodelerisanoxidativednadamageresponsefactor
AT ndanielberger chd6chromatinremodelerisanoxidativednadamageresponsefactor
AT martijnsluijsterburg chd6chromatinremodelerisanoxidativednadamageresponsefactor
AT corttgpiett chd6chromatinremodelerisanoxidativednadamageresponsefactor
AT fintanktstanley chd6chromatinremodelerisanoxidativednadamageresponsefactor
AT christophuschrader chd6chromatinremodelerisanoxidativednadamageresponsefactor
AT shujuanfang chd6chromatinremodelerisanoxidativednadamageresponsefactor
AT jenniferachan chd6chromatinremodelerisanoxidativednadamageresponsefactor
AT davidcschriemer chd6chromatinremodelerisanoxidativednadamageresponsefactor
AT zacharydnagel chd6chromatinremodelerisanoxidativednadamageresponsefactor
AT haicovanattikum chd6chromatinremodelerisanoxidativednadamageresponsefactor
AT aaronagoodarzi chd6chromatinremodelerisanoxidativednadamageresponsefactor
_version_ 1718381924581376000